T is generally assumed that in animal species all the sperm from a heterozygote, I though genetically different, have the same functional properties; consequently they cannot compete in fertilization, and no selection is possible. This has been interpreted as meaning that genes stop functioning after the first meiotic division (MULLER and SETTLES 1927). An exception to this principle has been d...

The RNA modification database provides a comprehensive listing of posttranscriptionally modified nucleosides from RNA, and is maintained as an updated version of the initial printed report [Limbach,P.A., Crain,P.F. and McCloskey,J.A. (1994) Nucleic Acids Res. , 22, 2183-2196]. Information provided for each nucleoside includes: the type of RNA in which it occurs and phylogenetic distribution; co...

In economics and other sciences, “statistical significance” is by custom, habit, and education a necessary and sufficient condition for proving an empirical result (Ziliak and McCloskey, 2008; McCloskey and Ziliak, 1996). The canonical routine is to calculate what’s called a t-statistic and then to compare its estimated value against a theoretically expected value of it, which is found in “Stud...

OBJECTIVE To measure Intensive Care Unit Research coordinator job satisfaction and importance and to identify priorities for role development. BACKGROUND Research coordinator numbers are growing internationally in response to increasing clinical research activity. In Australia, 1% of registered nurses work principally in research, many as Research coordinators. Internationally, the Associatio...