TOPIC: Diffuse Lung Disease TYPE: Fellow Case Reports INTRODUCTION: Sarcoidosis is a multisystem granulomatous disease whose etiology remains elusive yet nevertheless has classic pulmonary and extrapulmonary findings that may aid in the diagnosis. The proceeding case demonstrates however difficulty diagnosing this masquerader when rare presentations instead form clinical picture. CASE PRESENTAT...

Background Rheumatoid arthritis (RA) patients are at higher risk of developing cardiovascular (CV) diseases, both ischemic and non-ischemic, than the general population [1]. Inflammatory status fibrotic changes cardiac valves in these predispose them to a valve which could be detected by echocardiography [2]. Objectives To determine prevalence valvular regurgitation, according time disease evol...

In this Guest Editorial, Varinder Aggarwal, Zuowei Xie and Hajime Ito introduce the joint EurJOC/AsianJOC special collection on boron chemistry, which features original research review articles synthesis applications of organoboron compounds from researchers around world. This Special Collection From materials chemistry to pharmaceuticals, continue play a major role. Although topic may seem lik...

Background Polymyalgia rheumatica (PMR) is a chronic, inflammatory disorder characterized by aching and stiffness in the proximal regions of extremities elevated markers inflammation. PMR giant cell arteritis (GCA) are two conditions frequently coexisting [1,2], with increased incidence large vessel vasculitis aneurysm development found at long term follow-up. Furthermore, can be one manifestat...

Hysterectomy is one of the most frequently performed surgical procedures in the United States. Selection of the route of hysterectomy for benign causes can be influenced by the size and shape of the vagina and uterus; accessibility to the uterus; extent of extrauterine disease; the need for concurrent procedures; surgeon training and experience; average case volume; available hospital technolog...

The peptide 0~-agatoxin-IIIA (co-Aga-IIIA) blocks ionic current through L-type Ca channels in guinea pig atrial cells without affecting the associated gating currents, c0-Aga-IIIA permits the study of L-type Ca channel ionic and gating currents under nearly identical ionic conditions. Under conditions that isolate L-type Ca channel currents, 0~-Aga-IIIA blocks all ionic current during a test pu...

Background: Giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) are tightly associated inflammatory conditions of the elderly [1]. Both disorders can exhibit an increased articular vascular uptake 18-fluorodeoxyglucose (18-FDG) at positron emission tomography (PET)/computed (CT) scan [2]. Objectives: This study evaluated if large-vessel vasculitis (LVV) detected by PET/CT in patients wi...

Background The diagnosis of giant cell arteritis (GCA) is confirmed by temporal artery (TA) biopsy findings internal elastic lamina disruption, activated macrophages and T-lymphocytes infiltrating the arterial layers. immune microenvironment in GCA becomes T helper-1 polarized after steroid therapy consists potential anti-tumor cytokines including interferon-gamma (IFG) interleukin-12 (IL-12) w...

Background: Several cohort and case-control studies have suggested that overweight or obesity is associated with the risk of Rheumatoid Arthritis (RA). Associations were based on Body Mass Index (BMI), although this measurement does not reflect fat distribution [1]. Objectives: To study relationships between anthropometric measurements RA in women involved E3N cohort. Methods: an ongoing French...

Background Incident cases of giant cell arteritis (GCA) have a significantly reduced prevalence diabetes at time diagnosis (1) and lower fasting blood glucose, lipid levels body mass index compared to controls been found years before clinical [2,3]. This implicates metabolic pathways in the development GCA. Objectives To investigate relation between plasma proteins associated with metabolism su...