conclusions some results of the correlation coefficients are not the same with visualization. the reason may be due to the small number of data. materials and methods in the foundation-application study, we constructed two-way gene networks using nonparametric methods, such as spearman’s rank correlation coefficient and blomqvist’s measure, and compared them with pearson’s correlation coefficie...

Background: Stem cell therapy has been developed as an effective treatment method for the heart failure. Also, extracellular matrix has shown the positive effects in stem cell differentiation and myocardial tissue organization. Cardiogel is a native cardiac extracellular matrix (ECM) derived from cardiac fibroblasts. In the present study the role of cardiogel is examin...

Gene expression data have become increasingly important in machine learning and computational biology over the past few years. In field of gene analysis, several matrix factorization-based dimensionality reduction methods been developed. However, such can still be improved terms efficiency reliability. this paper, an innovative approach to feature selection, called Dual Regularized Unsupervised...

background: the association between interleukin‑6 (il‑6) (‑174g/c) gene polymorphisms and level of tissue breakdown and periodontal disease progression is unknown. the present study investigated quantitative parameters of interdental papilla in chronic periodontitis (cp) patients with il‑6 (‑174g/c) gene polymorphisms. materials and methods: sixty gingival samples were studied. after determinat...

in the present paper, we introduce the sequence space [{l_p}(e,delta) = left{ x = (x_n)_{n = 1}^infty : sum_{n = 1}^infty left|  sum_{j in {e_n}} x_j - sum_{j in e_{n + 1}} x_jright| ^p < infty right},] where $e=(e_n)$ is a partition of finite subsets of the positive integers and $pge 1$. we investigate its topological properties and inclusion relations. moreover, we consider the problem of fin...

Autosomal dominant polycystic kidney disease (ADPKD) is caused by a mutation in the disease1 (PKD1) gene, which responsible for 85% of ADPKD cases. The PKD1 gene encodes polycystin-1 (PC1) protein that has large extracellular area containing many polypeptide motifs. region PC1 includes several well-defined peptide domains show it been involved cell-cell and/or cell-matrix interactions. One regi...

The 5-upstream region of a winged bean chymotrypsin inhibitor gene (JVCI-3b) was found to have a high affinity for nuclear matrix. The region, named WCI-3b MAR (matrix attachment region), is highly A + T-rich and contains multiple sites interacting with nuclear matrix. A MAR was also found in the corresponding region of the WCI-x gene, another active gene of the WCI family. Several MAR-binding ...