OBJECTIVE To evaluate vertical forces in the pads of German Shepherd dogs by relative percentage among total limb vertical forces using a pressure sensitive walkway. PROCEDURE A pressure sensitive walkway was used to collect vertical force data for each pad of the limbs of 16 healthy client-owned German Shepherd dogs used for kinetic gait analysis. The vertical force for each pad was evaluate...

Abstract Chamomile ( Matricaria chamomilla L., Asteraceae) is one of the most important medicinal plants with antiphlogistic, spasmolytic, carminative, antibacterial and antimycotic properties. Thirty-one chloroplast markers were developed, optimised for high-resolution melting analysis. Subsequently, 23 M. accessions (247 individuals) complemented 2 individuals closely related species discoide...

ABSTRACT
 Objective: The aim of this study is to compare Matricaria chamomilla samples collected from nature and supplied pharmacies herbalists by performing quality control analyses investigate the antimicrobial activities them.
 Methods: These were examined according Matricariae flos monograph analysis in European Pharmacopoeia. Macroscopic microscopic examination, loss on drying to...

A simple and sensitive HPLC-UV method has been developed for the simultaneous determination of quercetin, luteolin, and apigenin in rat plasma after oral administration of Matricaria chamomilla L. extract. The flow rate was set at 1.0 ml/min and the detection wavelength was kept at 350 nm. The calibration curves were linear in the range of 0.11-11.36 μg/ml for quercetin, 0.11-11.20 μg/ml for lu...

The pharmacokinetics of diminazene aceturate following intramuscular (i.m.) administration at 4.2 mg/kg was evaluated in 8 healthy German Shepherd dogs. Blood samples were collected at 19 intervals over a period of 21 days. Diminazene plasma concentrations were measured using a validated HPLC method with UV detection and a sensitivity of 25 ng/ml. The in vitro and in vivo binding of diminazene ...

This experimental and dose-response curve study aimed to carry out the quality control of the Chamomilla recutita sample, as well as to estimate the ideal dose, for anti-inflammatory effect, of the extract of its capitula, in patients with phlebitis due to peripheral intravenous infusion of antineoplastic chemotherapy and to evaluate the toxicity of this extract in human beings. The therapeutic...