نتایج جستجو برای: maternal leptin

تعداد نتایج: 122227  

Journal: :Proceedings. Biological sciences 2009
Susannah S French Timothy J Greives Devin A Zysling Emily M Chester Gregory E Demas

The primary goal of virtually all organisms is to produce genetic offspring, thereby passing on their genes to future generations. Offspring production, however, is limited by available resources within an environment. Moreover, distributing sufficient energy among competing physiological systems is challenging and can result in trade-offs between self-maintenance and offspring investment when ...

Journal: :Archives of disease in childhood. Fetal and neonatal edition 2001
T K Hytinantti M Juntunen H A Koistinen V A Koivisto S L Karonen S Andersson

AIM To evaluate the effect of maternal diabetes on the concentrations of free and bound leptin at birth and during postnatal adaptation. METHODS Total, bound, and free leptin concentrations and the percentage of free leptin were measured in cord plasma and plasma at 3 days of age of 13 term infants of mothers with gestational diabetes mellitus (GDM) and 13 term infants of healthy mothers. Ges...

Journal: :The Journal of clinical endocrinology and metabolism 2001
J S O'Neil A E Green D E Edwards K F Swan T Gimpel V D Castracane M C Henson

Leptin, a product of both adipose tissue and the placental syncytiotrophoblast and a potential regulator of primate conceptus development, increases in the maternal circulation with advancing gestation. This increase may be potentiated by estrogens, which also increase as pregnancy progresses. In the present study adipose tissue was collected from nonpregnant (n = 5) baboons (Papio sp) and in b...

Journal: :Reproduction 2011
Laura C Schulz R Michael Roberts

The hormone leptin, which is primarily produced by adipose tissue, is a critical permissive factor for multiple reproductive events in the mouse, including implantation. In the CD1 strain, maternally derived leptin from the oocyte becomes differentially distributed among the blastomeres of pre-implantation embryos to create a polarized pattern, a feature consistent with a model of development i...

Journal: :Placenta 2004
J Zhao K L Townsend L C Schulz T H Kunz C Li E P Widmaier

In addition to effects on appetite and metabolism, the hormone leptin is required for reproduction in mammals. Maternal plasma leptin is increased above non-pregnant levels in all mammals thus far examined, including humans. The increase in plasma leptin appears to result in part from upregulation of adipose leptin secretion (e.g., in mice), or from production and secretion of leptin from the p...

2014
Nicholas J. Andreas Matthew J. Hyde Chris Gale James R. C. Parkinson Suzan Jeffries Elaine Holmes Neena Modi

BACKGROUND Maternal Body Mass Index (BMI) is positively associated with infant obesity risk. Breast milk contains a number of hormones that may influence infant metabolism during the neonatal period; these may have additional downstream effects on infant appetite regulatory pathways, thereby influencing propensity towards obesity in later life. OBJECTIVE To conduct a systematic review of stud...

Journal: :The Turkish journal of pediatrics 2004
Demet Toprak Ayşe Sevim Gökalp Sükrü Hatun Emine Zengin Ayşe Engin Arisoy Zeki Yumuk

Leptin is secreted from the edipose tissue and has an important role in the regulation of energy metabolism. This study aimed to compare serum leptin levels of preterm and full-term infants during the first three months of their life and to define the roles of sex, weight, thickness of subcutaneous adipose tissue, gestational age and maternal leptin in the determination of serum leptin levels. ...

Journal: :JPMA. The Journal of the Pakistan Medical Association 2001
G R Lakho K Nazir T Chundrigar N Jabeen M A Qureshi

OBJECTIVE To determine the serum leptin levels in Pakistani pregnant subjects at the time of delivery and to ascertain the relationship between serum leptin levels and related variables (weight, body mass index, placental weight, gestational age, parity) at delivery. SETTING Lady Dufferin Hospital, and Ziauddin Hospital Karachi. METHODS Leptin concentration was measured in 110 subjects from...

2017
Sambavi Kugananthan Zoya Gridneva Ching T. Lai Anna R. Hepworth Peter J. Mark Foteini Kakulas Donna T. Geddes

Human milk (HM) appetite hormones and macronutrients may mediate satiety in breastfed infants. This study investigated associations between maternal adiposity and concentrations of HM leptin, adiponectin, protein and lactose, and whether these concentrations and the relationship between body mass index and percentage fat mass (%FM) in a breastfeeding population change over the first year of lac...

Journal: :American journal of physiology. Regulatory, integrative and comparative physiology 2002
Richard A Ehrhardt Alan W Bell Yves R Boisclair

To better understand the biology of leptin during prenatal life, the developmental and spatial regulation of leptin was studied in ovine fetuses. Fetal plasma leptin increased steadily between days 40 and 143 postcoitus (PC), but it was unrelated to fetal weight or placental weight at day 135 PC. Leptin gene expression was detected in fetal brain and liver during most of gestation and in fetal ...

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