BACKGROUND We recently reported that ethanol and hexane extracts of the plant product, mastic gum (MG), contain constituents which can induce p53- and p21-independent G1-phase arrest followed by apoptosis of human HCT116 colon cancer cells in vitro. Herein, we extended these studies to investigate the in vivo anticancer activity of the hexane extract of MG (He-MG) against human colon tumor. The...

A micromechanical finite element (FE) framework was developed to predict the viscoelastic properties (complex modulus and creep stiffness) of the asphalt mixtures. The two-dimensional (2D) microstructure of an asphalt mixture was obtained from the scanned image. In the mixture microstructure, irregular aggregates and sand mastic were divided into different subdomains. The FE mesh was generated ...

In our research project entitled "Chemical irritative and/or genotoxic effect of fumes of bitumen under high processing temperatures on the airways," 73 mastic asphalt workers exposed to fumes of bitumen and 49 construction nonexposed workers were analyzed and compared with respect to polycyclic aromatic hydrocarbons (PAHs) exposure and exposure-related health effects. In order to assess the in...

This study presents micromechanical finite-element FE and discrete-element DE models for the prediction of viscoelastic creep stiffness of asphalt mixture. Asphalt mixture is composed of graded aggregates bound with mastic asphalt mixed with fines and fine aggregates and air voids. The two-dimensional 2D microstructure of asphalt mixture was obtained by optically scanning the smoothly sawn surf...

Exercise training causes increased oxidative stress. Pistacia Atlantica Extract (Mastic) is known to have a protective effect against oxidative stress and inflammation. We examined the effects of exercise training with and without Pistacia Atlantica extract administration on antioxidant markers in vistar rats. Twenty-eight Vistar female rats (six to eight weeks old, 150-200 g weight) allocate...

Pistacia lentiscus L. is a dioecious shrub or small tree with high drought resistance, native in the entire Mediterranean basin. The variety ‘Chia’ (mastic tree) cultivated for production of mastic gum (a resin produced after wounding trunks and thick branches) Island Chios (Greece), but it also has significant ornamental value. In present study, ten male female genotypes P. var. Chia from natu...