OBJECTIVE Angiogenesis or neovascularization has long been known to aid in progression and metastasis of malignant tumors. Tumor angiogenesis is a complex event mediated by angiogenic factors released from cancer cells and or by host immune cells. Mast cells may induce tumor progression and potentiate metastasis by stimulating angiogenesis. The purpose of the present study was to validate topog...

Objective: To evaluate the gastroprotective effects of β 3 -adrenoceptor agonists CGP 12177A and SR 58611A, on water immersion plus restraint stress (WIRS)-induced gastric ulceration in rats. Material and Methods: Drugs were administered (5, 10 and 15 mg/kg, p.o. ) 30 min prior to the ulcerogenic procedure. Ulcer index and the score for intensity of intraluminal bleeding were determined. Gastri...

objective(s) aristolochia indica has been widely used in the traditional medicine for the treatment of a variety of diseases. in the present study different extracts of roots of a. indica were evaluated for their anti­inflammatory, antipruritic and mast cell stabilizing activity. materials and methods anti-inflammatory activity was performed by compound 48/80 induced rat paw edema model and ant...

We used 21 years of acorn data from visual surveys of oak (Quercus spp.) trees (n 1⁄4 20,113) conducted in western North Carolina, USA, to develop predictive equations for hard-mast indices (HMIs) based on the proportion of trees bearing acorns (PBA). We calculated PBA using visual estimates of the percentage of oak crown with acorns (PCA), assigning acorn presence if PCA 33.5%. The proportion ...

abstract background and aims. reliable immunohistochemical assays to evaluate the definitive role of mast cells and angiogenesis in the pathogenesis of oral reactive lesions are generally not available. the purpose of the present study was to compare mast cell count (mcc) and microvessel density (mvd) between oral reactive lesions and evaluation of the correlation between mcc and mvd in these l...

The occurrence of mast cells is studied in the normal facial nerve and in the facial nerve post mortem exam of patients with chronic suppurative otitis media without associated facial paralysis. A small number of mast cells were found in the normal facial nerve. These cells were usually located in close proximity to the endoneural and epineural blood vessels. The number of mast cells was i...

Background & Objectives: Odontogenic cysts are among the most frequent destructive lesions of jaws which their pathogenesis and growth mechanism are not cleared. With respect to different roles of mast cells, they may play a role in the pathogenesis and growth of odontogenic cysts. The aim of present study was to evaluate mast cells in the most common odontogenic cyst. Methods:</e...