Contact lens induced ulcerative keratitis is a serious complication which can be devastating for the patient if treatment is delayed. Extended wear is the commonest cause of microbial keratitis in contact lens wear. New extended wear silicone hydrogel contact lenses have higher oxygen transmissibility so that they can be worn continuously for 30 days. They can also be used as bandage contact le...

Contact lens induced ulcerative keratitis is a serious complication which can be devastating for the patient if treatment is delayed. Extended wear is the commonest cause of microbial keratitis in contact lens wear. New extended wear silicone hydrogel contact lenses have higher oxygen transmissibility so that they can be worn continuously for 30 days. They can also be used as bandage contact le...

Experimental Acanthamoeba keratitis was induced in Wistar rats by intrastromal inoculation of Acanthamoeba polyphaga cysts. Keratitis developed in all corneas injected and was characterised by a diffuse granular opacity. The animals were examined for 70 days and a gradual reduction of keratitis was observed. Pathological sections showed liquefactive stromal necrosis and Acanthamoeba localised i...

OBJECTIVE To validate photographic bioimaging for evaluating the severity of herpes simplex virus keratitis. METHODS Stromal keratitis of patients in the Herpetic Eye Disease Study was clinically measured with a slitbeam micrometer and then photographed at trial entry. Calibrated images of 169 eyes were analyzed for the size, location, and density of stromal keratitis and endotheliitis, with ...

Keratitis is an inflammatory condition, characterized by involvement of corneal tissues. Most recurrent challenge of keratitis is infection. Bacteria, virus, fungus and parasitic organism have potential to cause infection. TLR are an important class of protein which has a major role in innate immune response to combat with pathogens. In last past years, extensive research efforts have provided ...

Due to impaired defensive mechanisms caused by injuries or little epithelial defects , different types of pathogens or environmental influences might induce corneal inflammation (keratitis). The form of corneal inflammation called superficial keratitis involves just the corneal surface (epithelium). If the inflammation involves corneal stroma it is called stromal or interstitial keratitis. Kera...

PURPOSE To report the use of corneal collagen crosslinking in the treatment of infective keratitis not responding to antimicrobial therapy. METHODS Two retrospective case reports of infective keratitis treated with corneal collagen crosslinking. RESULTS In both cases, corneal collagen crosslinking caused a rapid resolution of the infective keratitis, leaving residual stromal scarring. Due t...

Background & Aims: Exposure Keratitis (EK) is a common problem in critically ill patients admitted to the Intensive Care Unit (ICU). We conducted exposure keratitis in mechanical ventilatory patients in the intensive care unit of Imam Khomeini Hospital in Urmia for five years. Materials & Methods: In this retrospective cross-sectional study, the records of the patients were taken from the medi...

BACKGROUND Fungal keratitis is an important cause of corneal blindness all over the world. Although there are several reports on fungal keratitis from developing and developed countries, fungal keratitis in Ethiopia is poorly known. The aim of this study was to determine the prevalence of fungal keratitis and spectrum of fungi implicated in causing the infection. METHODS The present study was...

Pubmed and Medline were searched for articles referring to Pseudomonas keratitis between the years 2007 and 2012 to obtain an overview of the current state of this disease. Keyword searches used the terms "Pseudomonas" + "Keratitis" limit to "2007-2012", and ["Ulcerative" or "Microbial"] + "Keratitis" + "Contact lenses" limit to "2007-2012". These articles were then reviewed for information on ...