, 81 infliximab naive RA patients and 47 healthy subjects as controls. At the same time and apart from the purposes of that study, we also had done a pathergy test in those subjects who agreed to participate, with the aim of determining the effect of the pathergy phenomenon on the response of BS patients to the tuberculin test. Informed consent was obtained from all subjects. The study was appr...

INTRODUCTION Juvenile idiopathic arthritis (JIA) is characterized by synovial inflammation, followed by hyperplastic changes of the synovium, and destruction of articular cartilage along with underlying bone. This hyperplastic process is the result of inflammation-induced activation of NF-κB, which may be accompanied by decreased osteogenic differentiation of synovial mesenchymal progenitors an...

INTRODUCTION Maximum oxygen consumption shows the maximum oxygen rate of muscle oxygenation that is acceptable in many cases, to measure the fitness between person and the desired job. Given that medical emergencies are important, and difficult jobs in emergency situations require people with high physical ability and readiness for the job, the aim of this study was to evaluate the maximum oxyg...

RATIONALE AND OBJECTIVES Several statistical methods have been developed for analyzing multireader, multicase (MRMC) receiver operating characteristic (ROC) studies. The objective of this article is to increase awareness of these methods and determine if their results are concordant for published datasets. MATERIALS AND METHODS Data from three previously published studies were reanalyzed usin...

BACKGROUND The aim of this in vitro study was to evaluate the microindentation hardness and chemical composition of residual dentin left at the cavity bottom following removal of carious dentin using the Carisolv chemomechanical and Er:YAG laser caries excavation methods in comparison with the conventional tungsten-carbide bur excavation. METHODS Sixty-nine extracted permanent teeth with occl...

BACKGROUND Deaf or hard-of-hearing children experience difficulties in learning health principles. But technology has significantly improved their ability to learn. The challenge in e-learning is to design attractive applications while having an educational aspect. OBJECTIVE The aims of this study were to determine the pedagogical effectiveness of a health education application for deaf and h...

Penelitian ini bertujuan menganalisis perbedaan kepuasan kerja karyawan berdasarkan karakteristik individu yang terdiri dari jenis kelamin, tingkat pendidikan dan masa kerja. dilakukan pada PT. Aditya Mandiri Sejahtera. Jumlah sampel digunakan sebanyak 90 orang menggunakan sampling jenuh. Hasil uji normalitas menunjukkan data tidak terdistribusi normal. Oleh karena itu, maka metode analisis ada...

We studied the effects of adverse conditions such as constant light (LL) on the circadian rhythm of malate (MDH, EC 1.1.1.37) and lactate (LDH, EC 1.1.1.27) dehydrogenase activities of the testes of male Wistar rats on postnatal day 28 (PN28), anxiety-like behavior (elevated plus-maze test) at PN60 and sexual behavior at PN120. The rats were assigned to mother groups on day 10 of pregnancy: con...

“Supplementary Figure 1. Effect of activity blockade on synaptic area, levels of Homer and Bassoon, Homer-Bassoon colocalization values in three independent experiments, and the relationship between the colocalization values and synaptic properties. (A) TTX treatment does not affect the size of synaptic clusters. P > 0.05, Mann-Whitney test. (B) TTX treatment increases synaptic levels of Homer....

there are some barriers for rangers to take part in range plan projects andevaluation. their participation is very useful for range managers to plan and provide solutionsfor solving problems. this study aims at comparing barriers of participating from rangers andexperts point of view in lar moor rangelands, tehran, iran. in this research, data werecollected based on documentation-library and fi...