نتایج جستجو برای: malic

تعداد نتایج: 2561  

2003

The occurrence of malic acid in fermented products derived from various fruit juices is common knowledge and it has been generally supposed that this substance was exclusively derived from malic acid preformed in the fruit. The object of the following communication is to establish the fact that I-malic acid is a true product of fermentation by yeast and that significant amounts of the acid are ...

Journal: :The Journal of rheumatology 1995
I J Russell J E Michalek J D Flechas G E Abraham

OBJECTIVE To study the efficacy and safety of Super Malic, a proprietary tablet containing malic acid (200 mg) and magnesium (50 mg), in treatment of primary fibromyalgia syndrome (FM). METHODS Twenty-four sequential patients with primary FM were randomized to a fixed dose (3 tablets bid), placebo controlled, 4-week/course, pilot trial followed by a 6-month, open label, dose escalation (up to...

Journal: :Journal of biochemistry 1991
C Y Su H Lardy

Feeding the thermogenic steroid, 5-androsten-3 beta-ol-17-one (dehydroepiandrosterone, DHEA) in the diet of rats induced the synthesis of liver mitochondrial sn-glycerol 3-phosphate dehydrogenase to levels three to five times that of control rats within 7 days. The previously reported enhancement of liver cytosolic malic enzyme was confirmed. The induction of both enzymes was detectable at 0.01...

2011
Nafiseh Darandeh Ebrahim Hadavi

Citric acid is a regular ingredient in many vase solution formulations but pre-harvest use of citric acid is a novel method in vase life extension of cut flowers, which is reported on tuberose earlier. In order to verify previous result, and check for possible substitution of citric acid by malic acid, the current research was designed. Citric acid (0, 0.075, 0.15% w/v) and malic acid (0, 0.075...

Journal: :The Journal of biological chemistry 1990
K J Petty B Desvergne T Mitsuhashi V M Nikodem

We have studied the rat malic enzyme gene as a model for thyroid hormone (triiodothyronine (T3)) regulation of transcription. Our previous studies showed that transcription of this gene is controlled by T3 in vivo. In this study, we used COS-7 cells in culture to determine the location of a T3 response element (TRE) within this gene. Cotransfection of the rat T3 alpha-receptor cDNA with a repor...

Journal: :International journal of systematic bacteriology 1999
A Groisillier A Lonvaud-Funel

DNA sequences covering 36% of the mle gene that encodes the malolactic enzyme were determined for 13 strains of lactic acid bacteria, representing Pediococcus, Leuconostoc, Lactobacillus and Oenococcus genera. The sequences were aligned with the corresponding region of mleS in Lactococcus lactis. The phylogenetic distance matrix tree of all mle sequences was compared with the 16S rRNA phylogene...

2003
H. D. Dakin

The occurrence of malic acid in fermented products derived from various fruit juices is common knowledge and it has been generally supposed that this substance was exclusively derived from malic acid preformed in the fruit. The object of the following communication is to establish the fact that I-malic acid is a true product of fermentation by yeast and that significant amounts of the acid are ...

Journal: :The Journal of biological chemistry 2001
Y Wang L Yin F B Hillgartner

Triiodothyronine (T3) stimulates a robust increase (>40-fold) in transcription of the malic enzyme gene in chick embryo hepatocytes. Previous work has shown that optimal T3 regulation of malic enzyme transcription is dependent on the presence of an accessory element (designated as region E) that immediately flanks a cluster of five T3 response elements in the malic enzyme gene. Here, we have an...

Journal: :Structure 1999
Y Xu G Bhargava H Wu G Loeber L Tong

BACKGROUND Malic enzymes catalyze the oxidative decarboxylation of malate to pyruvate and CO2 with the concomitant reduction of NAD(P)+ to NAD(P)H. They are widely distributed in nature and have important biological functions. Human mitochondrial NAD(P)+-dependent malic enzyme (mNAD-ME) may have a crucial role in the metabolism of glutamine for energy production in rapidly dividing cells and tu...

2016
Jiao Xue Lan Wang Lin Zhang Srinivasan Balamurugan Da-Wei Li Hao Zeng Wei-Dong Yang Jie-Sheng Liu Hong-Ye Li

BACKGROUND The fast growing photosynthetic microalgae have been widely used in aquaculture, food, health, and biofuels. Recent findings in the diatom has proposed a pivotal role of NADP-malic enzyme in generation of NADPH as an important supply of reducing power for fatty acid biosynthesis. To test the lipogenic malic enzyme for fatty acid synthesis in green algae, here the malic enzyme gene Pt...

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