Introduction:The hippocampus is one for the major centers of learning and memory. Role of the opioid system has been investigated and on the other hand receptors related to this system such as mu-opioid receptors (MOR) are extended in the hippocampus. In this study the effect of Naloxone administration as a mu opioid receptor antagonist on passive avoidance memory in adult male rats was i...

Background Diabetes mellitus has a variety of structural and functional effects on the male reproductive system. Diabetes results in reduced sperm parameters and libido. The present study aims to investigate the effects of royal jelly (RJ) on reproductive parameters of testosterone and malondialdehyde (MDA) production in diabetic rats. MaterialsAndMethods This experimental study was conducted o...

SUMMARY The c arcinogenicity of N-hydroxy-2-fluorenyl benzenesulfonamide (N-HO-2-FBS), a potent carcinogen for the young male and female rat by i.p. administration, was confirmed by p.o. administration of the compound to the adult male rat. The compound produced hepatic lesions that were macroscopically and microscopically very similar to those induced by N-hydroxy-2-fluorenylacetamide. Examina...

Glutathione (GSH) conjugation of trichloroethylene (Tri) to form S-(1,2-dichlorovinyl)glutathione (DCVG) has been implicated in the nephrotoxicity and nephrocarcinogenicity of Tri. Marked sex- and species-dependent differences exist, however, in the susceptibility to Tri-induced renal toxicity, with the male rat being the most susceptible. The present study, therefore, focuses on potential diff...

Figure Legend: Figure 1 Oral mucosa, Gingiva Ectopic tissue, Sebaceous gland in male F344/N rat from a chronic study. There are clusters of sebaceous glands in the gingiva. Figure 2 Oral mucosa, Gingiva Ectopic tissue, Sebaceous gland in male F344/N rat from a chronic study (higher magnification of Figure 1). The clusters of sebaceous glands in the gingiva are adjacent to a dilated duct. Figure...

GH has diverse physiological actions and regulates the tissue-specific expression of numerous genes involved in growth, metabolism, and differentiation. Several of the effects of GH on somatic growth and gene expression are sex dependent and are regulated by pituitary GH secretory patterns, which are sexually differentiated. The resultant sex differences in plasma GH profiles are particularly s...

Atherosclerosis is arterial wall’s disease initiated by lipid retention, oxidation, and modification, provoking chronic inflmmation ultimately causing stenosis thrombosis. This study investigated the effect of alpha lipoic acid (ALA) on thoracic aorta type 2 diabetic rat. Fifteen adult male rat Rattus novergicus Wistar strain were separated into three groups (n=5), there labelled as control, di...