BACKGROUND We evaluated the impact of using ICSI for assisted fertilization on first trimester survival rates of singleton gestations among an unselected infertile population. METHODS The 1244 singleton gestations achieved by ICSI were segregated according to underlying infertility aetiology, with 55.0% having male factor, 3.6% endometriosis, 4.3% polycystic ovarian disease, 9.1% tubal factor...

BACKGROUND The aetiology of human male fertility, with impairment of sperm number, motility and morphology (oligoasthenoteratozoospermia), has been difficult to understand, partly for lack of animal models. METHODS An ethylnitrosourea (ENU) mutagenesis strategy has been successful in producing heritable gene mutations with phenotypes similar to human male infertility, and here, we describe th...

context air pollution is common in all countries and affects reproductive functions in men and women. it particularly impacts sperm parameters in men. this meta-analysis aimed to examine the impact of air pollution on the quality of sperm. conclusions the results of this meta-analysis showed that air pollution reduces sperm motility, but has no impact on the other sperm parameters of spermogram...

OBJECTIVE To determine whether particular semen characteristics in various clinical diagnoses of infertility are associated with high oxidative stress and whether any group of infertile men is more likely to have high seminal oxidative stress. Reactive oxygen species (ROS) play an important role in sperm physiological functions, but elevated levels of ROS or oxidative stress are related to male...

Objective. There is an asymmetric allocation of technology and other resources for infertility services. Intrauterine insemination (IUI) is a process of placing washed spermatozoa transcervically into the uterine cavity for treatment of infertility. This is a review of literature for the potential use of IUI as a basic infertility treatment in technology-limited settings. Study design. Review o...

Specialist infertility practice was studied in a group of 708 couples within a population of residents of a single health district in England. They represented an annual incidence of 1.2 couples for every 1000 of the population. At least one in six couples needed specialist help at some time in their lives because of an average of infertility of 21/2 years, 71% of whom were trying for their fir...

Many studies have focused on male infertility. There is limited evidence about the influence of nutrition on quality of semen. Approximately, 30-80% of infertility cases are caused by oxidative stress and decreased level of seminal total antioxidant capacity. This study was aimed to review the effects of oral antioxidant supplements on improving major semen parameters such as sperm concentratio...

Male infertility has become a very serious problem in the human reproduction system, but the molecular mechanism of infertility remains largely unknown. Fertilization is the phenomenon in which a sperm and oocyte find each other, interact, and fuse. Sperm-oocyte fusion-related factors on the sperm side play crucial roles in male infertility. For example, IZUMO1 is well-known as a sperm protein ...

The prevalence of male infertility appraised 10-15% in worldwide. Male infertility is frequently coupled to deficient in sperm development and production (1). Of note, in principle of the number of sperm cells in seminal fluid, has been categorised in azoospermia, severe oligozoospermia and mild oligozoospermia. In azoospermia condition, a sperm cell counts approximately ≤5×10 cells/mL, and in ...

Female infertility was reported to account for about 55% of cases, male factor accounted 30% 40% cases and unexplained the remaining 5 percent 15 cases. In Africa, infections resulting in tubo-peritoneal oligo-azoospermia (low sperm count) are most common causes infertility. Infertility is widespread Sub-Saharan Africa ranging from 13–17 countries with pockets high prevalence at 32%. The genera...