Background: Cytosolic double-stranded RNA (dsRNA) is an important ‘molecular signature’ for the detection of intracellular viral infections. Although intracellular dsRNA is a known potent inducer of apoptosis, the optimal time and dose for the onset of dsRNA-mediated apoptosis have not been studied in detail. Objective: To perform an accurate temporal assessment of the cell death responses in d...

The role of alveolar macrophages in the production of granulocyte/ macrophage colony-stimulating factor(s) by the rat lung was investigated. Lavaged lungs, when incubated at proper weight per volume of culture medium, produced the same amount of colony-stimulating factor as unlavaged ones. Both lavaged and unlavaged lungs produced similar types of colony-stimulating factor (s). Prolonged i...

the macrophages role within the tumor microenvironment has amended by a variety of factors, thus serves a vital role in tissue morphogenesis. the role of macrophages in health and disease differs enormously as the macrophage has shown dual functions. macrophage has a basic role in antigen presentation serving as the first line of defense in diseases. however the presence of cytokines and growth...

AMA Li X, Cai H, Wu W, Si S, Zhu M. Exposure duration of ambient fine particulate matter determines the polarization macrophages. Central European Journal Immunology. 2023. doi:10.5114/ceji.2023.130978. APA Li, X., Cai, H., Wu, W., Si, S., & Zhu, (2023). https://doi.org/10.5114/ceji.2023.130978 Chicago Xiangru, Hongyan Wei Shaoyan and Minli Zhu. "Exposure macrophages". Harvard MLA Xiangru et al...

The armadillo could be considered as an experimental model for leprosy studies. Mycobacterium leprae main host cells are macrophages and Schwann cells. However, endocytosis and germicidal activities of armadillo macrophages and monocytes have not yet been evaluated. The aim of this research was to evaluate endocytosis and NBT-reduction activities of monocyte-derived macrophages (MDM) and monocy...

Two groups of antibodies against mouse resident alveolar and peritoneal macrophages have been raised individually in rabbits by immunization with whole cell suspensions of lavaged alveolar and peritoneal macrophages. The whole antisera reacted positively with neutrophils and lymphocytes. However, upon extensive absorptions with these cells the activity became restricted to macrophages. The...

Background: Despite advances toward an improved understanding of the evasive mechanisms leading to the establishment of cystic echinococcosis, the discovery of specific immunosuppressive mechanisms and related factors are of great interest in the development of an immunotherapeutic approach. Objective: To elucidate immunosuppressive effects of bioactive factors contained in chromatographic frac...

objective(s) previous studies have demonstrated that the nitric oxide (no) dependent death of murine peritoneal macrophages activated in vitro with ifn-g and lps is mediated through apoptosis. in the present study, we investigated the synergistic effect of lps, ifn-g and iron on no production and apoptosis. materials and methods after determination of iron cytotoxicity, the peritoneal macrophag...

Human macrophages are reprogrammed by graphdiyne oxide from M2 to M1 macrophages, leading degradation of GDYO through a peroxynitrite-driven pathway with subsequent modulation pro-inflammatory cytokines including IL-1?.