objective: this study was aimed to examine the antinociceptive and anti-inflammatory effects of urtica dioica leaf extract in animal models. materials and methods: hydroalcoholic extract of the plant leaves was prepared by percolation method. male swiss mice (25-35 g) and male wistar rats (180-200 g) were randomly distributed in control, standard drug, and three experimental groups (n=6 in each...

conclusions these results indicate the lipid-lowering effects of quince leaf similar to atorvastatin and it can probably serve as a new potential natural product for atherosclerosis treatment. results oral administration of cholesterol for 8 weeks resulted in a significant increase (p < 0.05) in plasma markers. treatment with the extract at dose of 50 mg/kg and 0.5 mg/kg of atorvastatin not onl...

rosmarinus officinalis has been used in traditional medicine extensively. this study evaluated the hormonal and cellular effects of rosmarinus officinalis extract on testes of adult rats. thirty male wistar rats (in three groups) received 50 or 100 mg/kg b.w of rosmarinus officinalis extract (made from the plant’s leaves, flower and stem) (treatment groups) and 10 ml/kg b.w normal saline (contr...

due to the limited availability of effective pharmaceutical products and serious side effects of the available therapy for leishmaniasis, search for useful medicinal plants is necessary. previous studies reported preventative effect of echinacea against leishmania infections through immunologic stimulation. here we tested concentrated ethanolic extract of the root of echinacea purpurea prepared...

pomegranate (punica granatum l.), lythraceae, is mainly grown in mediterranean region. it is one of the major cultivated productions of iran, which have been used in folk medicine for many centuries. it has been proved that pomegranate has a high antioxidant activity and is effective in the prevention of atherosclerosis. this study compares the antioxidant activity, total phenolic and flavonoid...

conclusions due to phenolic content, methanolic extract of m. piperita has moderate antibacterial and antifungal properties against the aforementioned gram positive and gram negative bacteria and fungi strains. materials and methods the methanolic extract was prepared by standard procedure, and total phenol, total flavonoid, and total anthocyanin content were determined using a spectrophotomete...

background & aim:vaginal disease has always been a great concern of women. medicinal plants as natural resources with fewer side effects can effectively treat these infections given the diversity of these infections, resistance to antibiotics and side effects of existing drugs. the present study aimed to compare antimicrobial effects of methanol extract of francoeuria undulata on growth of seve...

background: emergence of drug resistance has brought major problems in chemotherapy. using nutrients in combination with chemotherapy could be beneficial for improvement of sensitivity of tumors to drug resistance. soybean-derived isoflavones have been suggested as chemopreventive agents for certain types of cancer, particularly breast cancer. in this study, the synergistic effects of soy isofl...

in iranian traditional medicine, there are some report regarding the anticonvulsant effect of ferula gummosa boiss. in this study, anticonvulsant activity, neurological deficits and lethality of the root acetone extract of this plant were evaluated in mice. the extract exhibited dose-dependent prevention of tonic seizures induced by pentylenetetrazole (ed50 = 154.4 mg/kg). however, the extract ...

introduction: renal ischemia reperfusion is considered to be one of the causes of acute renal failure (aki). in addition, renal ischemia is an important incident usually occurs due to renal transplantion, repair of suprarenal aneurysm, hemorrhagic shock. a recent study reported that reactive oxygen species (ros) are important mediators of aki. it seems essential to use antioxidant to decrease t...