We show that the manifold $(\mathbb{S}^2 \times \mathbb{S}^2) \operatorname{\#} (\mathbb{S}^2 \mathbb{S}^2)$ does not admit a non-constant non-injective uniformly quasiregular self-map. This answers question of Martin, Mayer, and Peltonen, provides first example quasiregularly elliptic which is elliptic. To obtain result, we introduce conformally formal manifolds, are closed smooth $n$-manifold...

Caldesmon inhibits myosin ATPase activity; phosphorylation of caldesmon reverses the inhibition. The caldesmon kinase is believed to be mitogen-activated protein (MAP) kinase. MAP kinases are activated during vascular stimulation, but a cause-and-effect relationship between kinase activity and contraction has not been established. We examined the role of MAP kinase in contraction using PD-09805...

Aging-related weakness is due in part to degeneration within the central nervous system. However, it is unknown how changes to the representation of corticospinal output in the primary motor cortex (M1) relate to such weakness. Transcranial magnetic stimulation (TMS) is a noninvasive method of cortical stimulation that can map representation of corticospinal output devoted to a muscle. Using TM...

Conformally Stäckel manifolds can be characterized as the class of $n$-dimensional pseudo-Riemannian $(M,G)$ on which Hamilton–Jacobi equation $$ G(\nabla u, \nabla u) = 0 for null geodesics and Laplace $-\Delta\_G , \psi 0$ are solvable by R-separation variables. In particular case in metric has Riemannian signature, they provide explicit examples metrics admitting a set $n-1$ commuting confor...

background and aims: the antioxidant and anti-inflammatory effects of carvacrol were reported. the aim of the current study was an investigation the relaxant effects of carvacrol on acetylcholine-induced contraction in isolated rat's ileum. materials and methods: in this study, the tissues separated from ileum were fixed on the organ bath containing tyrode's solution. the amplitude of...

The concept of substructural logic was originally introduced in relation to limitations Gentzen’s structural rules Contraction, Weakening and Exchange. Recent years have witnessed the development logics also challenging Tarskian properties Reflexivity Transitivity logical consequence. In this introduction we explain recent two aspects which it leads a reassessment bounds classical logic. On one...

Let G be a real noncompact semi-simple Lie group with finite center and K a maximal compact sub-group. The symmetric space M = G/K carries a measure invariant under the action of G. The operators which map L(p)(M) continuously into itself and commute with the action of G, can be easily characterized when p = 2 or p = 1. This note gives some results on "singular integrals" which map L(p) into it...

The effects of an opioid agonist, [d-Ala2]methionine enkephalinamide (DAME), administered into the rostral ventrolateral medulla (rVLM) or caudal ventrolateral medulla (cVLM) on cardiovascular responses to isometric muscle contraction were determined in anesthetized rats. A 30-s contraction evoked by tibial nerve stimulation increased mean arterial pressure (MAP) and heart rate (HR) by 34 ± 6 m...

Introduction: Thymol has negative ionotropic effect on heart and has direct effect on calcium release from sarcoplasmic reticulum. Some of the herbal plants just like carum copticum consist of thymol. The postganglionic neurons of the gastrointestinal parasympathetic system are located mainly in the myenteric and submucosal plexuses. Stimulation of these parasympathetic nerves causes general...

Meir and Keeler in 1 considered an extension of the classical Banach contraction theorem on a complete metric space. Kirk et al. in 2 extended the Banach contraction theorem for a class of mappings satisfying cyclical contractive conditions. Eldred and Veeramani in 3 introduced the following definition. Let A and B be nonempty subsets of a metric space X. A map T : A ∪ B → A ∪ B, is a cyclic co...