Prior work has shown that mild alkaline hydrolysis of nuclei previously extracted with cold dilute acid and with lipid sol vents yielded not only the expected RNA nucleotides but also free adenine and guanine in amounts which varied in versely with the extent of preliminary lipid extraction. The nucleic acid of the nuclei was identified as the source of the free purines. The experiments describ...

The acute degenerative alterations produced in lymphoid tissue of several species following a single injection of glycogenic adrenal cortical steroids, and the concomittant lymphopenia, were described in detail by Dougherty and White."' Subsequently, numerous investigators have been concerned with the biochemical effects of these steroid hormones on lymphoid tissue in efforts to elucidate the m...

Received: May 26, 2004 Accepted: September 15, 2004 Neoplastic diseases have not been widely studied in pigs, although prevalence in slaughter animals has been recorded in several countries in the past four decades. Since most swine are slaughtered at 6 months of age or younger, the most common tumors diagnosed are those that commonly occur in young animals, ie, lymphosarcoma, nephroblastoma, a...

LTERATIONS in serum protein demonstrable by electrophoretic analysis have been noted fairly frequently in cases of lymphosarcoma, lymphocytic leukemia and Hodgkin’s disease. Abnormal proteins such as cryoglobulins and myeloma-type proteins also have been observed in the serum of an occasional patient with these conditions. in this study we attempted to determine whether disturbances in serum gl...

An enzyme preparation obtained from bovine lymphosarcoma tissue catalyzes the DNA-dependent synthesis of RNA. Native DNA is a more efficient primer in the reaction than heat-denatured DNA.