Relatively little is known about the relationship of lymphoid-associated gene expression to the proliferation and differentiation potential of early human bone marrow lymphoid progenitors. Surface expression of interleukin-7 (IL-7) receptor-alpha (IL-7R alpha), a component of the high-affinity receptor for the lymphoid precursor growth factor IL-7, defined a CD34+ progenitor subset lacking the ...

Hypereosinophilic syndrome (HES) is a condition with diverse clinical presentation and prognosis. Due to its rarity, it often under-recognized. We present 48-year-old female patient who presented eosinophilic pneumonia bullous pemphigoid; rare skin manifestation of HES. It was considered as primary HES after comprehensive evaluation excluded secondary causes. However, picture laboratory makers ...

Taking into account the special role of oxidative stress that increases during cancer chemotherapy, effect antioxidant emoxipine on peripheral blood mononuclears was studied under conditions simulate cytotoxic effects antimetabolites a number modified cytidine nucleosides in relation to tumor cell line K562. Lymphoid cells were also source for subsequent modelling immune response cancer. It fou...

The prevalence of lymphoid follicles in endoscopic biopsy specimens from normal antral mucosa (n = 220), mucosa with reflux gastritis (n = 104), and in cases with Campylobacter pylori-associated gastritis (n = 2544) was studied. In the latter group whether there were associations between degree and activity of gastritis and the prevalence of lymphoid follicles and between the occurrence of lymp...

Histopathological examination of the ichthyotic skin showed perivascular dermal lymphoid cell infiltration in the superficial dermis and nodular and dense lymphoid cellular infiltration in the deep dermis. Lymphoid cells were CD3+ and CD20with a loss of CD7 expression. There were numerous (>25%) large, anaplastic cells with CD30 positivity among the lymphoid infiltrate. Clonal expansion of T ce...

Lymphoid and myeloid lineage segregation is a major developmental step during early hematopoiesis from hematopoietic stem cells. It is not clear, however, whether multipotent progenitors (MPPs) adopt a lymphoid or myeloid fate through stochastic mechanisms, or whether this process can be regulated by extracellular stimuli. In this study, we show that lymphoid lineage specification occurs in MPP...

Significant advances have been made in the field of immunophysiology since Selye discovered that acute stressors reduce the size of lymphoid organs. It is known that a variety of hormones other than glucocorticoids affect functional activities of lymphoid cells and macrophages. This paper summarizes recent findings of the effects of glucocorticoids and other hormones on lymphoid cells of domest...

1. Hansen SV, Nyvold CG, MH. Mantle cell lymphoma and the evidenceof an immature lymphoid component. Leuk Res. 2022;115:106824. doi: 10.1016/j.leukres.2022.106824. CrossRef Google Scholar

autoimmune lymphoproliferative syndrome (alps) is a rare, inherited disorder of immune dysregulation secondary to defective lymphocyte apoptosis. this leads to uninhibited proliferation of lymphoid tissue manifesting with lymphadenopathy, hepatosplenomegaly, autoimmune cytopenia, and an increased risk of lymphoid malignancy. we report a 2 year old boy with fever, generalized lymphadenopathy, he...