OBJECTIVE Children with ventricular septal defects (VSD) can have chronic volume overload, which can result in changes of left heart echocardiographic parameters. To evaluate the changes before and after surgical closure, the children were divided into three groups according to the degree of mitral regurgitation (MR), and their echocardiographic characteristics were reviewed at serial follow-up...

Catheter ablation has been shown to improve left ventricular (LV) ejection fraction (LVEF) in patients with atrial fibrillation (AF) and heart failure (HF). Our aim was assess the impact of AF on outcome HF LV systolic dysfunction. We performed a retrospective observational cohort study all LVEF <50% no apparent cause for dysfunction other than who underwent catheter tertiary referral center be...

We tested the hypothesis that chronic treatment with sildenafil attenuates myocardial infarction (MI)-induced heart failure. Sildenafil has potent protective effects against necrosis and apoptosis following ischemia-reperfusion in the intact heart and cardiomyocytes. ICR mice underwent MI by left anterior descending coronary artery ligation and were treated with sildenafil (0.71 mg/kg bid) or s...

To compare the hemodynamic effects of a calcium-channel blocker with those of a conventional vasodilator in the awake preinstrumented dog, diltiazem and nitroprusside were administered in equihypotensive infusions before (decrease in mean aortic pressure by 10%; p less than .001, n = 6) and after (decrease in mean aortic pressure by 12%; p less than .001) chronic volume overload (CVO) produced ...

ATP-sensitive potassium channels play an important role in myocardial electrical activity. Genetic disruption of these channels predisposes the myocardium to cardiac diseases. Herein we investigated whether two polymorphisms, E23K and I337V, located in the Kir6.2 subunit of ATP-sensitive potassium channels are associated with dilated cardiomyopathy (DCM) in a Chinese population. Blood was colle...

Ilemodynamic and echocardiographic measurements were obtained in 15 patients prior to cardioversion and immediately, one, three, and five hours after ca ,dioversion of atrial fibrillation to normal sinus rhythm1z4. j ve hours after cardioversion, there was improvement in cardiac index (P < 0.005), in stroke index (P <0.005)1and i11 stroke work index (P < 04)25), but no significant change in hea...

Purpose: To evaluate the coronary thrombolytic effect of atorvastatin plus percutaneous intervention (PCI) for treatment acute myocardial infarction.Methods: From April 2019 to October 2020, 88 patients with infarction who were treated in Zhangqiu District People's Hospital randomly assigned receive either PCI (conventional group) or (combined group). Myocardial injury index, TnI, and creatine ...

Abstract Funding Acknowledgements Type of funding sources: None. Background Kidney transplantation (KT) improves the hemodynamic burden associated with volume overload, and anemia in patients chronic kidney disease, but cardiovascular disease remains leading cause death after KT. This study evaluated longitudinal change eccentric concentric myocardial remodeling its impact on outcomes Methods A...

BACKGROUND The systemic effects of absorbed glucose degradation products (GDPs) contained within the conventional peritoneal dialysis solutions (cPDS) are largely unknown, while they appear to affect also cardiovascular function. The aim of the present study was to evaluate if the new bicarbonate-based less bioincompatible new peritoneal dialysis solutions ameliorate cardiac structural and func...

the present study attempted to compare the structural and functional changes of left heart ventricle in female basketball players of khuzestan superior league (aged between 18 and 29) during regular training and long-term detraining. out of 30 female players, 15 subjects were assigned randomly to regular training group and 15 subjects to long-term detraining group. the structural and functional...