Arterial hypertension is a major risk factor for congestive heart failure. Left ventricular (LV) hypertrophy is often associated with arterial hypertension and characterizes subjects with a particularly elevated risk of untoward cardiovascular events, including heart failure.1 LV hypertrophy is, in turn, associated with impaired LV myocardial contractility and LV diastolic dysfunction. LV hyper...

BACKGROUND Allograft dysfunction is a common finding early after heart transplant (HT). We sought to assess the recovery of left (LV) and right ventricular (RV) function during the first year after HT in children and young adults using pulsed-wave tissue Doppler imaging. METHODS AND RESULTS We analyzed serially performed echocardiography in 44 pediatric HT recipients (median age: 7.3 years at...

introduction left ventricular (lv) twist is believed to store potential energy and plays an important role in generating diastolic suction. recent advances in echocardiography techniques have allowed quantification of lv twist. the aim of the present study was to compare lv twist and torsion in healthy human subjects determined by velocity vector imaging (vvi) and tissue doppler imaging (tdi) a...

Different patterns of left-ventricular (LV) diastolic dysfunction were reported in patients with pulmonary hypertension (PHT). There are no data regarding the relationship between the severity of PHT and LV diastolic dysfunction. In order to determine the severity of PHT at which LV diastolic dysfunction occurs and to identify its pattern, we studied by Doppler echocardiography 120 patients wit...

This study was performed to validate echocardiographic and Doppler techniques for the assessment of left ventricular (LV) diastolic function in spontaneously hypertensive rats (SHR) and normotensive Wistar rats. In 11 Wistar rats and 20 SHR, we compared 51 sets of invasive and Doppler LV diastolic indexes. Noninvasive indexes of LV relaxation were related to the minimal rate of pressure decline...

BACKGROUND Hypertension and age are recognized as important risk factors for left ventricular (LV) diastolic dysfunction. Some studies have shown that diabetes itself may also be an independent risk factor for LV diastolic dysfunction, although this is controversial. The aim of this study was to determine the factors associated with LV diastolic dysfunction in patients with type 2 diabetes in t...

The effects of isoproterenol were examined in 10 conscious, chronically instrumented adult dogs with left ventricular (LV) failure after pressure overload hypertrophy induced by aortic banding at 8-10 weeks of age (LV free wall plus septum-to-body weight ratio, 8.6 +/- 0.5 g/kg) and also in eight control dogs (LV free wall plus septum-to-body weight ratio, 5.1 +/- 0.3 g/kg). Baseline values of ...

Background Chronic right ventricular (RV) pressure and volume overload in pulmonary arterial hypertension (PAH) results in leftward shift of the interventricular septum and impaired left ventricular (LV) diastolic function. However, the impact of PAH-mediated interdependency on LV fluid mechanics and fluid/structure interactions in LV diastolic dysfunction is incompletely understood. 4D flow CM...

Background Dyspnea with exertion is a common symptom in patients with left ventricular (LV) systolic and diastolic dysfunction. Assessing changes in systolic and diastolic hemodynamic parameters with exercise is necessary to thoroughly characterize these patients. Evaluation of changes in LV systolic function with exercise stress cardiac magnetic resonance (MR) has been demonstrated previously ...