Podocytopathy in systemic lupus erythematosus is characterised by diffuse foot process effacement without significant peripheral capillary wall immune deposits as seen on electron microscopy. Lupus podocytopathy falls outside the scope of the current International Society of Nephrology and the Renal Pathology Society classification of lupus nephritis. We present a case of relapsing podocytopath...

The lupus anticoagulant was found in the plasma of 31 of 60 patients with systemic lupus erythematosus and other connective tissue disorders (mixed connective tissue disease, systemic vasculitis, polyarteritis nodosa, primary sicca syndrome, discoid lupus, Behcet's syndrome, and systemic sclerosis). Strong associations were found with biological false positive seroreaction for syphilis and thro...

The diagnostic significance of anti-double-stranded deoxyribonucleic acid (anti-dsDNA) determination was evaluated in a prospective manner from 1974 to 1982 in a group of 441 patients without systemic lupus erythematosus whose sera were found to contain antibodies to dsDNA on routine screening (Farr assay). Within one year 69% (304) of these patients fulfilled the preliminary American Rheumatis...

1. Martín JM, Ramón D, Monteagudo C, Llombart B, Castelló A, Molina I, et al. Lupus eritematoso cutáneo subagudo inducido por fármacos. Actas Dermosifiliogr. 2004;95:117--9. 2. Callen JP. Drug-induced subacute cutaneous lupus erythematosus. Lupus. 2010;19:1107--11. 3. Marzano AV, Vezzoli P, Crosti C. Drug-induced lupus: an update on its dermatologic aspects. Lupus. 2009;18:935--40. 4. Callen JP...

The objective of this article is to identify common and atypical features of systemic lupus erythematosus diagnosed following hepatitis B vaccination. We analyzed retrospectively the medical records of 10 systemic lupus erythematosus patients from different centers, who developed the disease following hepatitis B vaccination and determined the prevalence of different manifestations and the time...

Systemic lupus erythematosus (SLE) is an episodic, potentially fatal, multisystem autoimmune disease characterized by the presence of antinuclear antibodies especially to double stranded DNA. Bullous systemic lupus erythematosus is an extremely rare subset of lupus erythematosus. We report a 10-year-old boy with bullous SLE and nephrotic syndrome.

Bullous systemic lupus erythematosus has rarely been described in pediatric lupus population and the real prevalence of childhood-onset bullous systemic lupus erythematosus has not been reported. From January 1983 to November 2013, 303 childhood-onset SLE (c-SLE) patients were followed at the Pediatric Rheumatology Unit of the Childreńs Institute of Hospital das Clínicas da Faculdade de Medicin...

In a disease with such widespread and variable manifestations as systemic lupus erythematosus the diagnosis, at least in the early stages, often depends upon a clinical suspicion supported by laboratory investigations, notably the demonstration of lupus erythematosus (L.E.) cells. While this test is highly specific for systemic lupus erythematosus it has these disadvantages. In a few patients L...

LET: lupus erythematosus tumidus SLE: systemic lupus erythematosus INTRODUCTION Lupus erythematosus tumidus (LET) is a nonscarring form of cutaneous lupus erythematosus that typically presents in middle-age men as urticariallike lesions on sun-exposed areas. There is a paucity of information on black patients with LET. To our knowledge, this case marks the fourth published report of LET in a bl...

UNLABELLED INTRODUCTION The occurrence of systemic lupus erythematosus has been only rarely reported in patients with sickle-cell disease. CASE PRESENTATION We describe the case of a 23-year-old North-African woman with sickle-cell disease and systemic lupus erythematosus, and discuss the pointers to the diagnosis of this combination of conditions and also present a review of literature. T...