Background Quantifying the temporal progression of key pathophysiological events in Alzheimer’s disease is crucial for staging disease, dementia risk assessment, and informing clinical trials. This work extends a novel algorithm (sampled iterative local linear approximation; SILLA) developed modeling PET trajectories to: 1) generate unified CSF amyloid accumulation timeline, 2) characterize bio...

A hurricane event can often produce both intense rainfall and a storm tide that cause major compound flooding threat to coastlines. This paper examined applications of multivariate copula-based time series models using data observed during Hurricane Irma (2017) along the coastlines Florida, Georgia, South Carolina, United States. Multivariate were developed bivariate copulas wherein modeled LOW...

Objective This study was intended to explore the relationship between level of serum phosphate and prognosis in septic patients. Methods Data were obtained from public database, which divided into 2 subgroups according whether they complicated with chronic kidney disease. Initial values extracted patients on admission hospital. Propensity score-matched analysis performed. The hypophosphatemia, ...

White mold, caused by Sclerotinia sclerotiorum (Lib.) de Bary, can be a serious disease of crops grown under cool, moist environments. In many plants, such as soybean [Glycine max (L.) Merr.], complete genetic resistance does not exist. To identify possible genes involved in defense against this pathogen, and to determine possible physiological changes that occur during infection, a microarray ...

Predictive maintenance strategies are becoming increasingly more important with the increased needs for automation and digitalization within pulp paper manufacturing sector.Hence, this study contributes to examine most efficient pre-processing approaches predicting sensory data trends based on Gated Recurrent Unit (GRU) neural networks. To validate model, from two presses several methods utiliz...

BACKGROUND Discharge destination after critical illness is increasingly recognized as a valuable patient-centered outcome. Recently, vitamin D status has been shown to be associated with important outcomes such as length of stay (LOS) and mortality in intensive care unit (ICU) patients. Our goal was to investigate whether vitamin D status on ICU admission is associated with discharge destinatio...