BACKGROUND Low-carbohydrate, high-animal protein diets, which are advocated for weight loss, may not promote the desired reduction in low-density lipoprotein cholesterol (LDL-C) concentration. The effect of exchanging the animal proteins and fats for those of vegetable origin has not been tested. Our objective was to determine the effect on weight loss and LDL-C concentration of a low-carbohydr...

BACKGROUND Low-carbohydrate diets (LCDs) have been vastly popular for weight loss. The association between a low-carbohydrate dietary pattern and risk of gestational diabetes mellitus (GDM) remains unknown. OBJECTIVE We aimed to prospectively examine the association of 3 prepregnancy low-carbohydrate dietary patterns with risk of GDM. DESIGN We included 21,411 singleton pregnancies in the N...

PURPOSE OF REVIEW There has been continued interest in the physiological, nutritional and clinical aspects of low-carbohydrate diets. This review will discuss the effects on appetite regulation, metabolic parameters, body weight and body composition, the role of glycemic index and glycemic load, as well as long-term outcomes. RECENT FINDINGS Low-carbohydrate, high-protein diets appear to impr...

Following a low carbohydrate diet, there is a shift towards more fat and less carbohydrate oxidation to provide energy to skeletal muscle, both at rest and during exercise. This review summarizes recent work on human skeletal muscle carbohydrate and fat metabolic adaptations to a low carbohydrate diet, focusing mainly on pyruvate dehydrogenase and pyruvate dehydrogenase kinase, and how these ch...