In the present study, we aimed to detect microRNA-9 (miR-9) expression level and its clinical significance in laryngeal squamous cell carcinomas (LSCC). 103 patients who were diagnosed with LSCC and treated between March 2010 and June 2013 were enrolled in this study. Expression levels of miR-9 were detected by real-time quantitative RT-PCR assay. Survival curves were estimated using the Kaplan...

Recurrent event time data are common in biomedical follow-up studies, in which a study subject may experience repeated occurrences of an event of interest. In this paper, we evaluate two popular nonparametric tests for recurrent event time data in terms of their relative efficiency. One is the log-rank test for classical survival data and the other a more recently developed nonparametric test b...

The logrank test is a well-known nonparametric which often used to compare the survival distributions of two samples including right-censored observations, it also known as Mantel-Haenszel test. Gρ family tests, generalizes by using weights assigned observations. In this paper, we present switch monotonicity property for was motivated need derive bounds statistic in case imprecise data This sta...

Survival analysis is widely applied in many fields such as biology, medicine, and public health. A typical analysis of survival data involves the modeling of time-to-event data, such as the time until death. To find Survival probabilities of the given observations censored or not, use Kaplan-Meier methods of estimation. But this method gives survival probabilities at any specific time. So this ...

objective the mortality of patients with locally advanced triple-negative breast cancer (tnbc) is high, and pathological complete response (pcr) to neoadjuvant chemotherapy (nac) is associated with improved prognosis. this retrospective study was designed and powered to investigate the ability of 18f-fluorodeoxyglucose positron emission tomography/computed tomography (fdg-pet/ct) to predict pat...

BACKGROUND Alkaline phosphatase (ALP) removes phosphate groups from many types of molecules. The aim of the present research was to study the relation between plasma ALP and survival in diabetic patients with myocardial infarction. METHODS Retrospective study: from 954 admissions (15 months period) in a coronary care unit, we selected 200 admissions corresponding to 195 patients with myocardi...

We use the empirical likelihood method to derive a test and thus a confidence interval based on the rank estimators of the regression coefficient in the accelerated failure time model. Standard chi-squared distributions are used to calculate the p-value and to construct the confidence interval. Simulations and examples show that the chi-squared approximation to the distribution of the log empir...