In multiple fields of study, access to the circulatory system in laboratory studies is necessary. Pharmacological studies in rats using chronically implanted catheters permit a researcher to effectively and humanely administer substances, perform repeated blood sampling and assists in conscious direct measurements of blood pressure and heart rate. Once the catheter is implanted long-term sampli...

Critically ill patients who require renal replacement therapy (RRT) are vulnerable to catheter-related bloodstream infections (CRBSI). This study compared the risks of dialysis catheter infection according to the choice of locking solution in the intensive care unit (ICU). A prospective quasi-experimental study with marginal structural models (MSM) and 2:1 greedy propensity-score matching (PSM)...

Flushing and locking of intravenous catheters are thought to be essential in the prevention of occlusion. The clinical sign of an occlusion is catheter malfunction and flushing is strongly recommended to ensure a well-functioning catheter. Therefore fluid dynamics, flushing techniques, and sufficient flushing volumes are important matters in adequate flushing in all catheter types. If a cathete...

Despite the advocation of fistula first strategy, over 80 % incident dialysis patients initiate with tunnelled catheters (TDC) and 30 remain catheter dependent. related blood stream infection (CRBSI) is a dreaded complication reported incidence rate 1.1 to 5.5 per 1000 days. Conventionally management CRBSI includes IV antibiotics along antibiotic lock solution. this 30-50 require removal, espec...

Medical researchers at Department of Infectious Diseases and Microbiology at the Stamford Hospital in Stamford, CT are studying episodes of central venous catheter-related bacteremia (CVCB) that have become common events in patients with long-term indwelling central venous catheter use. Since no standardized treatment of CVCB exists, novel approaches have been used to salvage infected catheters...

OBJECTIVE To evaluate the evidence regarding the use of ethanol lock therapy (ELT) for catheter-related bloodstream infection (CRBSI) prophylaxis and treatment. DATA SOURCES A literature search was conducted using PubMed (August 2003-January 2013) with search terms: ethanol lock, ethanol locks, ethanol lock therapy, prophylaxis, prevention, catheter-related bloodstream infection, and catheter...

Since the first description in 1982, totally implanted venous access ports have progressively improved patients' quality of life and medical assistance when a medical condition requires the use of long-term venous access. Currently, they are part of the standard medical care for oncohematologic patients. However, apart from mechanical and thrombotic complications, there are also complications a...

BACKGROUND AND OBJECTIVES Elderly patients require tunneled central vein dialysis catheters more often than younger patients. Little is known about the risk of catheter-related bloodstream infection in this population. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS This study identified 464 patients on hemodialysis with tunneled central vein dialysis catheters between 2005 and 2007 and exclude...