Little information is available about the usefulness of concurrent chemoradiotherapy for locally advanced thymic carcinoma due to a rare anterior mediastinal tumor. We experienced a case of locally advanced thymic carcinoma that responded well to concurrent thoracic radiotherapy combined with cisplatin plus vinorelbine chemotherapy. The patient showed remarkable tumor regression and has remaine...

Management of locally advanced colon cancer metastases is challenging and operation carries an increased risk of morbidity and mortality. The knowledge of exact sites of involvement can aid the surgeon to make a decision regarding complete resection or palliative therapy. PET/CT scan is an advantage in this setting because metabolic alterations often precede the anatomic changes; moreover, it c...

C l i n M e d International Library Citation: Denlinger N, Nolan N, Bixel K, Salani R, Martin D, et al. (2015) Interstitial Brachytherapy for Locally Advanced Cervical Cancer. Int J Womens Health Wellness 1:003 Received: September 16, 2015: Accepted: October 19, 2015: Published: October 21, 2015 Copyright: © 2015 Denlinger N. This is an open-access article distributed under the terms of the Cre...

Locally advanced cervical cancers comprise a large majority of the gynecologic cancers in India and other developing countries. Concurrent chemo-radiation has improved the survival of high risk stage I and stage II cervical cancers. There is no evidence that the same survival benefit has been achieved with chemo-radiation in stage III and stage IV disease. Interferon-alpha and Retinoic acid hav...

PURPOSE Brachytherapy plays a major role in the treatment of patients with carcinoma of the cervix. However, routine intracavitary brachytherapy may not be feasible or adequate to treat locally advanced disease. The purpose of this retrospective study (spanning a 20-year period) was to determine the outcome of interstitial low-dose-rate brachytherapy in the treatment of bulky or locally advance...

AIMS To evaluate the predictive value of the nuclear DNA content (image cytometry) and p53 overexpression (immuno-histochemistry using antibody CM-1) in uniformly treated stage I carcinomas of the mobile tongue. Also, to compare stage I carcinomas with advanced tongue carcinomas (stages II-IV). METHODS Archival formalin fixed, paraffin wax embedded tumour specimens from 54 patients with stage...

Neoadjuvant chemotherapy followed by surgery (NCS) has not been fully evaluated clinically. Currently, the main regimen of neoadjuvant chemotherapy (NAC) used in NCS includes cisplatin. The antitumor effects of NAC reduce lymph node metastasis and the tumor diameter in patients prior to surgery, and this can reduce the number of high risk patients who require postoperative radiation therapy. Ma...

background: renal cell carcinoma is the third most common urological cancer. surgical resection is still the mainstay of treatment for this tumor. here we present a new surgical approach for the management of locally advanced renal cell carcinoma. methods: we chose ten patients with extensive renal masses. the patient, under general anesthesia after preparation and draping, was placed in the su...

background: worldwide, cervical cancer is one of the most challenging gynecologic cancers in treatment. objectives: this study was designed with the aim of comparing patients treated with external beam radiotherapy (ebrt) and interactivity brachytherapy (icbt) with ebrt and extrafascial hysterectomy in locally advanced stages of cervical cancer (iib-iii). patients and methods: the present study...