abstract background: in 1958, silverman demonstrated that maintenance ofbody temperature reduces mortality in low birth weight infants. from the early 1990s it was already recognized that adequate environmental warmth was essential in the case of newborns. however, neonatal hypothermia continues to be a significant issue in developing countries. methods: in order to describe the incidence and s...

Background: Neonatal deaths mostly occur within the first one week and first 24 hours of life from a variety of conditions. Objective: To examine the role of significant hypothermia and hypoglycaemia, in addition to some other factors, in neonatal mortality occurring within the first 24 hours of admission.Methods: A prospective study of newborn infants hospitalized within the first 24 hours of ...

INTRODUCTION AND OBJECTIVES Abnormal QT interval durations and dispersions have been associated with increased risk of ventricular arrhythmias. The present study examines the possible arrhythmogenic effect of inducing QT interval variations through local epicardial cooling and warming. METHODS In 10 isolated rabbit hearts, the temperatures of epicardial regions of the left ventricle were modi...

Background: Asphyxia is a perinatal accident with a high mortality rate, therapeutic hypothermia in both head or whole body was suggested as effective therapeutic methods. In this study, we compare these methods in neonates with asphyxia.Methods and Materials: 16 neonates with asphyxia in two hospitals including Alzahra(head hypothermia) and Taleghani hospital (total body hypothermia) went unde...

Objective(s):The mechanism of hypothermia action of acetaminophen (APAP) remains unclear even 125 years after its synthesis. Acetaminophen produces hypothermia. The mechanism of this reduction in core body temperature is not clear but evidence shows that it is not dependent on opioid and cannabinoid receptors. Because of strong documents about the roles of GABA and benzodiazepine receptors in h...

BACKGROUND Hypothermia has been shown to be neuroprotective in animal models of hypoxia-ischaemia. It is currently being evaluated as a potentially therapeutic option in the management of neonatal hypoxic-ischaemic encephalopathy. However, significant hypothermia has adverse systemic effects. It has also recently been found that the stress of being cold can abolish the neuroprotective effects o...