There have been some recent studies on the clinical uses of the antihistamines as local anesthetic agents (1, 2, 3, 4). These have included the use of the antihistamines as local anesthetics for minor surgical procedures, nerve blocks and spinal anesthesia. The authors have compared the particular antihistamines under evaluation to procaine and, in general, have obtained results superior to tho...

Local anesthetics are commonly used in the perioperative environment to facilitate surgical procedures or to provide postoperative pain management for patients. The use of local anesthetics, however, introduces the risk of complications resulting from local anesthetic systemic toxicity and the risks of increased morbidity and mortality for the surgical patient. Systemic toxicity from the inject...

Although local anesthesia usually is used in surgical procedures, field or nerve blocks can provide more effective anesthesia in some situations. In a field block, local anesthetic is infiltrated around the border of the surgical field, leaving the operative area undisturbed. In field blocks, epinephrine may be added to the anesthetic to enhance vasoconstriction and prolong the duration of anes...

One of the very real complications possible in the use of local anesthetic agents is a relative overdose of the drug, resulting in an inordinate and potentially dangerous serum level. Even when using strict and careful technique, problems can occur. The reactions cited in the aforementioned cases were most likely the result of the accidental intravenous injection of a local anesthetic agent. Tw...

BACKGROUND Two commonly used methods of digital nerve block with local anesthetic are the two-injection dorsal technique and the single-injection volar subcutaneous technique. The authors compared these two digital block techniques with respect to local anesthetic injection pain and recipient preference of anesthetic technique. METHODS Twenty-seven volunteers had the long finger of each hand ...

OBJECTIVES Local anesthetic infiltration is also a process of a painful process itself. INJEX™ technology, known as "Needle-free" drug delivery system, was designed for reducing the pain associated with cutaneous procedures. We conducted a prospective, randomized trial to evaluate the application of lidocaine with INJEX™ system and 27-gauge needle. METHODS A total of 60 consecutive patients w...

Although local anesthetics have an acceptable safety profile, significant morbidity and mortality have been associated with their use. Inadvertent intravascular injection of local anesthetics and/or the use of excessive doses have been the most frequent causes of local anesthetic systemic toxicity (LAST). Furthermore, excessive doses of local anesthetics injected locally into the tissues may le...

To purchase reprints, contact The InnoVision Group, 101 Columbia, Aliso Viejo, CA 92656. Phone, (800) 8092273 or (949) 362-2050 (ext 532); fax, (949) 362-2049; e-mail, [email protected]. patients given local anesthetics also receive intravenous sedatives such as benzodiazepines to relieve anxiety. One of the main risks of local anesthesia is local toxic effects caused by accidental intravascula...

objective: anesthetic techniques like the akinosi technique were introduced to surmount the problems of the conventional inferior alveolar nerve block (ianb) technique. this study aimed to compare the local anesthetic efficacy of ianb via the conventional and akinosi techniques in patients presenting to the maxillofacial surgery department of school of dentistry, shahid beheshti university. met...

BACKGROUND Local anesthetic injections are widely used in the emergency department for different purposes. Pain management for such injections is of great importance to both patients and the healthcare system. OBJECTIVES Our study aimed to determine the effectiveness and safety of cryotherapy in patients receiving local anesthetic injections. METHODS Subjects who presented with superficial ...