OBJECTIVE To study the recurrence of breast cancer among patients who were using the levonorgestrel-releasing intrauterine system (LNG IUS). DESIGN A retrospective, controlled cohort analysis. SETTING Six Belgian hospitals. PATIENT(S) We identified 79 breast cancer patients who used the LNG IUS, and we selected a control group of 120 patients with no history of LNG IUS use and who were cl...

The hydrostatic compression of piezoelectric single crystals of La(3)Nb(0.5)Ga(5.5)O(14) (LNG) and La(3)Ta(0.5)Ga(5.5)O(14) (LTG) was studied at pressures of up to 23 GPa in diamond-anvil high-pressure cells using single-crystal X-ray diffraction techniques. The reflection-intensity data for LNG and LTG were collected at pressures of up to 22.8 GPa and 16.7 GPa, respectively. Both compounds sho...

Global gas markets feature two types of suppliers: piped gas and LNG exporters. Pipelines have a high degree of “asset specificity”: once built, they are physically bound to a particular route. LNG is transported by tanker, with a choice of export markets. Put simply: LNG is mobile, pipelines are not. This paper uses game-theoretic modelling to show how its commitment to serving a single market...

Iran’s vast common natural gas resources and the necessity to extract and export it as Liquefied Natural Gas (LNG) to distances more than 3000Km opens a lucrative field for researchers to optimize LNG cycles. In this article heat integration in cryogenic cycles by determining interacycle partition temperature and optimizing refrigeration features like Subcooler, Presaturator, aftercooler, reboi...

INTRODUCTION Sub-dermal hormone implants, such as levonorgestrel (LNG), are a safe and desirable form of long-acting contraception, but their use among HIV-positive women on antiretroviral therapy (ART) may be compromised given the potential for a cytochrome P450 3A-mediated drug-drug interaction. Our study aimed to characterize the pharmacokinetics of LNG released from a sub-dermal implant ove...

The growing popularity of levonorgestrel (LNG)-releasing intra-uterine systems for long-acting reversible contraception provides strong impetus to define immunomodulatory properties of this exogenous progestin. In initial in vitro studies herein, we found LNG significantly impaired activation of human dendritic cell (DCs) and their capacity to promote allogeneic T cell proliferation. In follow-...

In operation of a large LNG processing plant there will be uncertainties related to planning and realization of an optimal operation strategy. Results show the importance of including the whole production chain in the optimization. For a test scenario where we look at the event of delayed ship arrival, this gives lower losses than a normal approach where the upstream part of the system and the ...

Energy plays a fundamental role in both manufacturing and services, and natural gas is quickly becoming a key energy source worldwide. Facilitating this emergence is the expanding network of ocean-going vessels that enable the matching of natural gas supply and demand on a global scale by transporting it in the form of liquefied natural gas (LNG) for eventual regasification at its destination. ...