OBJECTIVE : To assess the effects of preoperative systemic chemotherapy on remnant liver parenchyma, liver function, and morbidity after major liver resection for colorectal liver metastases. BACKGROUND : Many patients operated upon for colorectal cancer liver metastases receive previous chemotherapy. Whether systemic chemotherapy alters liver parenchyma in such way that it increases the risk...

INTRODUCTION The presence of liver cirrhosis goes along with a higher chance for the need of liver resection. As established laboratory parameters often underestimate the degree of cirrhosis this is associated with an increased risk for postoperative liver failure due to the preoperatively impaired liver function. Known liver function tests are unlikely to be performed in daily use because of h...

PURPOSE Many surgical patients are admitted to the intensive care unit (ICU), resulting in an increased demand, and possible waste, of resources. Patients who undergo liver resection are also transferred postoperatively to the ICU. However, this may not be necessary in all cases. This study was designed to assess the necessity of ICU admission. METHODS The medical records of 313 patients who ...

BACKGROUND/AIMS The effects of short-bowel syndrome on liver function and liver morphology independent of parenteral nutrition have not been thoroughly investigated. Our aim was to investigate the effects of massive bowel resection on hepatocyte apoptosis and liver function in rats. MATERIALS AND METHODS A total of 37 female Sprague-Dawley rats were randomly assigned to five groups: Control (...

INTRODUCTION Increasing evidence suggests that surgical resection may be offered to a subgroup of patients with liver metastasis of gastric adenocarcinoma. The aim of this case report is to illustrate the surgical resection of a single liver metachronous recurrence twelve months after a radical total gastrectomy for cancer. CASE REPORT A 63-year-old male patient with an Eastern Cooperative On...

INTRODUCTION Minimally invasive laparoscopic liver surgery is being performed with increased frequency. Lesions located on the anterior and lateral liver segments are easier to approach through laparoscopy. On the other hand, laparoscopic access to posterior and superior segments is less frequent and technically demanding. AIM Technical description for laparoscopic transthoracic access employ...

In 1952, Jean Louis Lortat-Jacob undertook the first successful extended right hepatectomy.It was pioneering surgery. Improvement in liver resection has been achieved in the past decade. Among other factors, a gradual change of technology, platforms and refinement of surgical techniques have played significant roles. In this review, the various surgical approaches, operative techniques, operati...