background: occupational lead poisoning is common in workers of some industries, but lead hepatotoxicity has rarely been reported. several animal studies have revealed lead induced liver damage but clinical studies concerning the manifestations of lead induced liver toxicity in humans are scares. this study was designed to investigate the clinical manifestations and pathological parameters of h...

patients and methods in the double-blind placebo study, 33 obese children with nafld from 2008 to 2009 were included. lifestyle intervention (balanced calorie diet, 1300-1800 kcal/d and physical activity) was prescribed to all. the patients were concurrently randomized to receive vitamin e 400 mg/d (n = 17)] or placebo (n = 16). results at the end of six months of therapy there was significant ...

at present, liver transplantation remains the only curative option for the patients with cirrhosis and end-stage liver diseases. the survival rate and recurrent diseases remain the major issues in the patient post-transplantation. unani medicine is one of the oldest traditional systems of medicine which has been treating chronic liver diseases and cirrhosis (talayyaful-kabid) for centuries. the...

background: including multivariate survival data can be pointed competing risks data. there are various methods to analyze such data such as semi-parametric methods of cause-specific hazard function, and cumulative incidence function. the aim of this study was to deploy competing risks model to analyze the determinants of patients with liver cirrhosis. materials and methods: during the one-year...

hepatitis b infection is the main cause of liver related mortality in many countries including iran. liver transplantation in cirrhosis due to hbv infection before 1990 was an absolute contraindication. recurrent infection was a significant event in post liver transplant setting and resulted in increased risk of graft failure and death except successful transplanted individuals. advances in ant...

background:methotrexate (mtx) is one of the most commonly used disease-modifying antirheumatic drugs in the treatment of rheumatoid arthritis (ra) which can be associated with toxic effects on different organs. this study was designed to investigate the hepatotoxic effects in ra patients treated with mtx. methods: in this cross-sectional observational study, ra patients who received standard do...

recognition of typhoid hepatitis is important since it has to be differentiated from other common ailments in our country such as viral, malarial or amoebic hepatitis. early institution of specific therapy in cases of typhoid hepatitis carries a good prognosis. in our study, 107 patients with positive blood or bone marrow cultures for salmonella typhi, were evaluated for hepatomegaly and abnorm...

background: the radioprotective effect of grewia asiatica fruit (gae) which contains anthocyanin type cyanidin 3- glucoside, vitamin c, a, minerals, carotenes and dietary fibers etc was studied. materials and methods: for study swiss albino mice were divided into five groups-1. control (vehicle treated) 2. gae treated (700 mg / kg. b.wt / day for fifteen days), 3. irradiated (5 gy), 4. gae + ir...

conclusions any discrepancy between histopathologic changes in time-zero biopsies and pattern of early liver laboratory alterations may be considered as a warning for causes other than pri. objectives the aim of this study was to show the correlation between histopathologic changes of pri and the alterations in liver tests in the early post-transplantation period. materials and methods between ...

results roc-derived spo2 threshold of ≤ 94% can predict hypoxemia (pao2 < 60 mmhg) with a sensitivity of 100% and a specificity of 95%. furthermore, there are associations between the roc-derived spo2 threshold of ≤ 97% and detection of hypoxemia (pao2 < 70 mmhg) with a sensitivity of 100% and a specificity of 46%. the accuracy of pulse oximetry was not affected by the severity of liver disease...