background: a great deal of evidence has indicated that oxidatively modified ldl plays a critical role in the initiation and progression of atherosclerosis. antioxidants that can prevent ldl oxidation may act as antiatherogens. copper is a candidate for oxidizing ldl in atherosclerotic lesions. the binding of copper ions to ldl is usually thought to be a prerequisite for ldl oxidation by copper...

introduction this paper proposes the concept of autonomous drug-encapsulated nanoparticle (adenp) as a novel non-invasive approach to prevent atherosclerosis. adenp consists of three simple units of sensor, controller (computing), and actuator. the hardware complexity of adenp is much lower than most of the nanorobots, while the performance is maintained by the synergism in the swarm architectu...

background: elevated serum levels of oxidized low-density lipoprotein (oxldl) have been found in type 2 and in poorly controlled diabetic patients. gestational diabetes mellitus (gdm) has common features with type 2 diabetes. objective: the aim of our study was to evaluate the serum levels of oxldl in women with gdm compared to normal pregnant women. materials and methods: in this cross-section...

background: in addition to the known risk factors of cardiovascular diseases, many studies reported that there are some new risk factors such as hemocystein, lipoprotein (a), fibrinogen and factor vп affecting the morbidity and increasing the risk of disease. the current study was designed to evaluate such risk factors in relation to those previously established in a case-control study design. ...

conclusions rs9364559 in the lpa gene may contribute to the risk of cad in the han chinese population; haplotypes which contain rs9346816-g were all associated with an increased risk of cad in this study. background mutations in the solute carrier family 22 member 3 (slc22a3), lipoprotein (a)-like 2 (lpal2), and the lipoprotein (a) (lpa) gene cluster, which encodes apolipoprotein (a) [apo (a)] ...

background : apolipoprotein e (apoe) gene encodes an important protein in reforming injuries of central nervous system (cns). it is assumed that various apoe alleles may be functionally different. the purpose of this study was to investigate the distribution of apoe genotypes in multiple sclerosis (ms) patients in a small cohort of iranians. methods : in this case-control study, blood samples o...

Background: Serum lipids abnormalities have been observed in various forms of cancers including acute leukemia. Investigators report decreased total cholesterol and HDL, and elevated triglyceride in leukemic patients. Limited studies had been performed to discover the correlation between abnormal lipids profile and disease activity in leukemic patients in Iran. This study was done to evaluate t...