نتایج جستجو برای: lipid pathway
تعداد نتایج: 464691 فیلتر نتایج به سال:
Although it is well known that low nitrogen stimulates lipid accumulation, especially for algae and some oleaginous yeast, few studies have been conducted in fungal species, especially on the impact of different nitrogen deficiency strategies. In this study, we use two promising consolidated bioprocessing (CBP) candidates to examine the impact of two nitrogen deficiency strategies on lipid prod...
The central role of mitochondria in metabolic pathways and in cell-death mechanisms requires sophisticated signalling systems. Essential in this signalling process is an array of lipid mediators derived from polyunsaturated fatty acids. However, the molecular machinery for the production of oxygenated polyunsaturated fatty acids is localized in the cytosol and their biosynthesis has not been id...
The immune response in atopic dermatitis (AD) is driven predominantly by T helper (Th2) cells. Th2-type cytokines interleukin (IL)-4, and IL-13 activate the Janus kinase/signal transduction activator of transcription (JAK-STAT) signaling pathway, which essential for their pro-inflammatory action detrimental effects on permeability barrier epidermis. lipid abnormalities have not been completely ...
The effect of resveratrol on the sphingolipid metabolism has been investigated in ras-transformed 3T3 fibroblasts. Resveratrol is a phytoalexin great medico-biological significance, which reported to exhibit significant beneficial effects such as antioxidant, lipid-lowering, anti-neoplastic, etc. Sphingolipids are functionally active lipid molecules, implicated important cellular processes, pro...
Parkinson’s Disease (PD) is a common and progressive neurodegenerative disorder characterised by motor impairments as well non-motor symptoms. While dopamine-based therapies are effective in fighting the symptoms early stages of disease, lack neuroprotective drugs means that disease continues to progress. Along with traditionally recognised pathological hallmarks dopaminergic neuronal death int...
Lipid A is a highly conserved component of lipopolysaccharide (LPS), itself a major component of the outer membrane of Gram-negative bacteria. Lipid A is essential to cells and elicits a strong immune response from humans and other animals. We developed a quantitative model of the nine enzyme-catalyzed steps of Escherichia coli lipid A biosynthesis, drawing parameters from the experimental lite...
In virtually every cell, neutral lipids are stored in cytoplasmic structures called lipid droplets (LDs) and also referred to as lipid bodies or lipid particles. We developed a rapid high-throughput assay based on the recovery of quenched BODIPY-fluorescence that allows to quantify lipid droplets. The method was validated by monitoring lipid droplet turnover during growth of a yeast culture and...
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