background: downy mildew caused by plasmopara halstedii is one of the most devastating diseases of sunflower worldwide. so far several dominant resistance genes designated as pl have been identified and their molecular markers linked to these genes are available. however, no information on the resistance genes is available in iranian lines. objective: in this study, the presence of three map-ba...

phenylketonuria (pku) is one of the most common metabolic inborn diseases caused by mutations in the phenylalanine hydroxylase (pah) gene. this gene is linked to a variable number of tandem repeats (vntr) region which is a polymorphic marker that facilitates the implementation of prenatal diagnosis and carrier screening. in this study, vntr with 13 repeats that has not been reported previously ...

Depression alone is a severe and acute disease, but its close relationship with neuroinflammation and neurodegenerative diseases has emphasized its importance. In fact, the linking bridges between depression and these diseases are cytokines, especially pro-inflammatory cytokines which have fundamental roles in organizing different parts of central nervous system and emotions. Studying the relat...

Tumour suppressor protein 53 (TP53 or simply p53) is a well known protein linked to apoptosis, cell signalling, cascading and several myriad functions in cells. Many diseases are linked to p53 though analysis show only 216 interaction partners. Whether p53 plays an important role in cardiovascular diseases (CVD) remains uncertain. Through this bioinformatical analysis, we propose that p53 might...