نتایج جستجو برای: line first
تعداد نتایج: 1762824 فیلتر نتایج به سال:
BACKGROUND Adherence to first-line antiretroviral therapy (ART) may be an important indicator of adherence to second-line ART. Evaluating this relationship may be critical to identify patients at high risk for second-line failure, thereby exhausting their treatment options, and to intervene and improve patient outcomes. METHODS Adolescents and adults (n = 436) receiving second-line ART were a...
2062 www.thelancet.com Vol 381 June 15, 2013 Access to antiretroviral therapy in low-income and middle-income countries has been scaled-up eff ectively in the past decade; however, failure of the fi rst-line regimen is increasing. In The Lancet, the SECOND-LINE Study Group provide a high-quality evidence-based strategy for safe and eff ective treatment of patients in whom fi rstline treatment h...
Background EULAR guidelines recommend switching to or adding a b/tsDMARD in patients with rheumatoid arthritis (RA) who do not respond have an inadequate response csDMARDs. Traditionally, TNF inhibitors (TNFi) are prescribed as the first b/tsDMARD. In Dec 2021, upadacitinib (UPA) label US was updated restrict use those had intolerance one more TNFi. Objectives period prior UPA change (through J...
BACKGROUND Evidence of reduced cardiovascular morbidity and mortality as well as cost support thiazide diuretics as the first-line choice for treatment of hypertension. The purpose of this study was to determine the proportion of senior hypertensives that received thiazide diuretics as first-line treatment, and to determine if cardiovascular and other potentially relevant comorbidities predict ...
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