results there were 39 cases with lymph node metastasis in 59 malignant tumors, and 0 cases in 6 benign follicular type tumors. the staining scores by jt-95 of the 39 tumors with lymph node metastasis were 5+ in eight cases and 6+ in 31 cases. on the other hand, the scores of 20 malignant tumors without lymph node metastasis were < 4+ in all of the cases. in the co-cultured assay, numerous adhes...

the production of murine monoclonal antibody (mab) has not yet been reported in iran. the present work describes for the first time the generation of several murine hybridoma clones secreting mabs directed against human leukocyte surface antigens. the secreted antibodies by hybridoma clones have been screened on different lymphoid and non-lymphoid tissues. results indicated that of seven hybrid...

herpes simplex virus types 1 (hsv-1) and 2 (hsv-2) are members of the herpesviridae family. about 40% to 80% of the world populations are infected with hsv and its prevalence is high in iran. the high prevalence of this virus in the community and the ability of the virus in causing fatal diseases among immunocompromised patients, have encouraged studies to be performed on hsv and suitable cell ...

Background: Breast cancer is the most common female malignancy and the leading cause of cancer mortality in women worldwide. The human epidermal growth factor receptor2 (HER2) is a transmembrane tyrosine kinase receptor that is usually overexpressed in human breast cancers. Stable cell lines heterogeneously overexpressing HER2 are highly required as in vitro models for breast cancer research. T...

based on the evaluation of two human cell lines, hela and chang, abeuploidy and several marker chromosomes were found in both cells. the morphological characteristic of marker chromosomes of chang cells was distinctly different from hela. certain submetacentric marker chromosome was frequently present among 80% of marker chromosomes of chang cells which distinguished this line from hela, which ...

Background: Radiation-induced bystander effect is a response which results in damage in non-irradiated cells in response to signals from the irradiated cells. The aim of the present study was to investigate microwave-induced bystander effect from a GSM mobile phone simulator on induction of apoptosis in Jurkat cell line. Materials and Methods: Jurkat cells were divided into three groups of non-...