BACKGROUND Service providers face difficult decisions about how best to develop services for the increasing numbers of young people with life-limiting conditions who require palliative care. OBJECTIVE To explore alternative short break and emergency respite care options to children's hospice care. METHODS A two-phase evaluation with young people, families and professionals. Phase 1: qualita...

OBJECTIVES Most deaths in U.S. PICUs occur after a decision has been made to limitation or withdrawal of life support. The objective of this study was to describe the clinical characteristics and outcomes of children whose families discussed limitation or withdrawal of life support with clinicians during their child's PICU stay and to determine the factors associated with limitation or withdraw...

Head, Department of Medicine and Cardiology, Central Railway Headquarters Hospital, Mumbai 400027 newer therapeutic options like Cardiac Synchronization Therapy (CRT) in Heart Failure and Automated Implantable Cardioverter-Defibrillator (AICD) which have given improved quality of life and better morbidity and mortality benefits, but at a cost which may be a big limiting factor in developing nat...

In the recent popular press much discussion has been made of a new group of ‘super bugs’ that are emerging from India and Pakistan. These organisms have a specific resistance gene designated as NDM-1 (New Delhi metallo-β-lactamase-1). The gene encoding this β-lactamases associated with organisms that demonstrate multiple antimicrobial resistance profiles, limiting the treatment options for thes...

Hirayama disease is a rare disorder seen in young patients their second or third decade of life with slowly progressive self-limiting distal upper limb muscle weakness seldom symmetrical involvement. It peculiar anterior horn cell that managed conservatively limited surgical options available as per literature.

Allelopathy arises from the release of chemicals by one plant species that affect other species in its vicinity, usually to their detriment. Allelopathic effects have been demonstrated to be limiting factors for species distributions and ecological processes in some natural or agricultural communities. Based on the biphasic hormetic responses of plants to allelochemicals, ecological-limiting-fa...

Ocular graft-versus-host disease (GVHD) is a common complication that occurs after allogeneic transplantation. It can cause severe dry eyes that are described as having a burning, gritty, and painful sensation. Ocular GVHD can affect quality of life by causing pain and photophobia, limiting activities of daily living (e.g., reading, watching television), compromising safety while driving, and p...

Objective- Trigonella foenum graecum, (Fenugreek) has anti-inflammation, antiseptic and antidiabetic activities in traditional medicine. This study was performed to investigate the protection effects of Fenugreek seed extract on the experimental reflux esophigitis (RE) in rats. Design- experimental study. Animals- 24 male Wistar albino rats. Procedures- Rats were randomly allocated into 4 group...