A method is proposed to detect whether a given enzyme catalyzes a rate-limiting step in a metabolic pathway. With the use of a range of concentrations of specific inhibitors of an enzyme, the finding of a biphasic response with an initial null effect indicates the non-rate-limiting nature of the enzyme. With this method, phosphoenolpyruvate carboxykinase is indicated to catalyze a rate-limiting...

To our knowledge, no one has explored the effect of modifications in balance recovery instructions on the kinetics of the threshold of balance recovery. In particular, the effect of instructions limiting the number of steps on joint torques at the maximum lean angle has not been quantified. We determined the joint torques at the ankle, knee and hip of 28 younger adults recovering balance at the...