The recent hype surrounding the antimelanogenic properties of glutathione has resulted in physicians frequently administering it as a "wonder" drug for skin lightening and treatment of hyperpigmentation, especially in ethnic populations with darker skin tones. This phenomenon has seen a recent surge owing to aggressive marketing and capitalization of pharma-cosmeceutical companies. However, the...

This paper introduces the optimization algorithm to improve search rate in urban path routing problems using viral infection and local search in urban environment. This algorithm operates based on two different approaches including wavelet transform and genetic algorithm. The variables proposed by driver such as degree of difficulty and difficulty traffic are of the essence in this technique. W...

Augmented Downhill Simplex Method (ADSM) is introduced here, that is a heuristic combination of Downhill Simplex Method (DSM) with Random Search algorithm. In fact, DSM is an interpretable nonlinear local optimization method. However, it is a local exploitation algorithm; so, it can be trapped in a local minimum. In contrast, random search is a global exploration, but less efficient. Here, rand...

  The clustering problem under the criterion of minimum sum of squares is a non-convex and non-linear program, which possesses many locally optimal values, resulting that its solution often falls into these trap and therefore cannot converge to global optima solution. In this paper, an efficient hybrid optimization algorithm is developed for solving this problem, called Tabu-KM. It gathers the ...

In this paper an integrated lot-sizing and scheduling problem in a flexible job shop environment with machine-capacity-constraint is studied. The main objective is to minimize the total cost which includes the inventory costs, production costs and the costs of machine’s idle times. First, a new mixed integer programming model,with small bucket time approach,based onProportional Lot sizing and S...

Gravitational search algorithm (GSA) is one of the newest swarm based optimization algorithms, which has been inspired by the Newtonian laws of gravity and motion. GSA has empirically shown to be an efficient and robust stochastic search algorithm. Since introducing GSA a convergence analysis of this algorithm has not yet been developed. This paper introduces the first attempt to a formal conve...

Gravitational search algorithm (GSA) is one of the newest swarm based optimization algorithms, which has been inspired by the Newtonian laws of gravity and motion. GSA has empirically shown to be an efficient and robust stochastic search algorithm. Since introducing GSA a convergence analysis of this algorithm has not yet been developed. This paper introduces the first attempt to a formal conve...

Today, with rapid growth of the World Wide Web and creation of Internet sites and online text resources, text summarization issue is highly attended by various researchers. Extractive-based text summarization is an important summarization method which is included of selecting the top representative sentences from the input document. When, we are facing into large data volume documents, the extr...