Understanding neural functions inevitably involves arguments traversing multiple levels of hierarchy in biological systems. However, finding new components or mechanisms of such systems is extremely time-consuming due to the low efficiency of currently available functional screening techniques. To overcome such obstacles, we utilize pan-neuronal calcium imaging to broadly screen the activity of...

This paper uses trace-driven simulations to evaluate the performance of different cache management techniques for multi-level Web proxy caching hierarchies. In particular, the experiments consider heterogeneous cache replacement policies within a two-level caching hierarchy, and sizebased partitioning across the levels of a caching hierarchy. Three different synthetic Web proxy workloads are us...

Waddington's (1942) notion of canalization has been widely invoked in developmental psychology to conceptualize species-typical regularities in behavioral development as genetically determined. In contrast, a developmental systems view, such as the one described in the present article, sees the genes as only one component in a hierarchy of influences, all of which contribute to canalize behavio...

The uses-hierarchy of a Smalltalk program’s packages is not generally available to its maintainer. This sets the stage for a common error extending a low level package in a way that makes it depend on a higher level package. Such a mistake introduces a cyclic dependency, which prevents the low level package, and all others in the cycle, from being reused independently. This paper describes a to...

Diagnosis and repair of failed process executions is an important task for almost any process oriented application. Because in practice complete specifications of process activities are not available, diagnosis and repair methods for partial behavior models are of great importance. We show that if the assumption of complete behavioral models is lifted, basic diagnosis and repair problems reside...

System optimization techniques based on efficient dynamic reconfiguration have been widely adopted in recent years. Cache reconfiguration is a promising optimization technique for reducing memory hierarchy energy consumption with little or no impact on overall system performance. While cache reconfiguration is successful in desktop-based and embedded systems, it is not directly applicable in re...

This paper introduces hot potato high level synthesis transformation techniques. These techniques add deflection operations in the behavioral description of a computation in such a way that the requirements for two important components of the final implementation cost, the number of registers and the number of interconnects, are significantly reduced. Moreover, it is shown how hot potato techni...

background accident investigation programs are a necessary part in identification of risks and management of the business process. objectives one of the most important features of such programs is the analysis technique for identifying the root causes of accidents in order to prevent their recurrences. analytical hierarchy process (ahp) was used to compare management oversight and risk tree (mo...