نتایج جستجو برای: leukotriene antagonists

تعداد نتایج: 55425  

Journal: :iranian journal of allergy, asthma and immunology 0
"saeid fallah-tafti davood mansouri mohammad reza masjedi mehran marashian delara faridian "

the tetrad of bronchial asthma, severe sinusitis, nasal polyp, eosinophilia, and systemic vasculitis is the main feature of allergic granulomatosis and angitis (churg- strauss syndrome). this vasculitis is usually seen idiopathic in patients with a long history of asthma; oral steroids using steroid inhalers, vaccination and desensitization might be triggering factors. drugs such as leukotriene...

2016
Ming-Ju Tsai Ping-Hsun Wu Chau-Chyun Sheu Ya-Ling Hsu Wei-An Chang Jen-Yu Hung Chih-Jen Yang Yi-Hsin Yang Po-Lin Kuo Ming-Shyan Huang

Previous in vitro and in vivo studies have demonstrated the potential of using cysteinyl leukotriene receptor antagonists (LTRAs) for chemoprevention, but this has not been investigated in any clinical setting. We therefore investigated the chemopreventive effect of LTRAs in a nationwide population-based study. From the Taiwan National Health Insurance Research Database, we enrolled adults with...

2014
Srinivas Bandaru Vijaya Kumar Marri Priyadarshani Kasera Purnima Kovuri Amandeep Girdhar Deepti Raj Mittal Sabeen Ikram Ravi GV Anuraj Nayarisseri

Montelukast and Zafirlukast are known leukotriene receptor antagonists prescribed in asthma treatment. However, these fall short as mono therapy and are frequently used in combination with inhaled glucocorticosteroids with or without long acting beta 2 agonists. Therefore, it is of interest to apply ligand and structure based virtual screening strategies to identify compounds akin to lead compo...

Journal: :Allergologia et immunopathologia 2009
S Rodrigues Carvalho I Silva P Leiria-Pinto J Rosado-Pinto

leukotrienes in mast cells. Although no reported measurements of leukotrienes in patients with mastocytosis between or during clinical flares are available, anecdotal reports suggest a transient response to leukotriene antagonists used to treat recalcitrant symptoms. Symptomatic relief has been observed within the first month of treatment but tends to wane thereafter. The role of leukotriene re...

2009
Graziano Riccioni Alessandra Zanasi Nicola Vitulano Barbara Mancini Nicolantonio D'Orazio

Atherosclerosis represents an important chronic inflammatory process associated with several pathophysiological reactions in the vascular wall. The arachidonic acid, released by phospholipase A2, is an important substrate for the production of a group of lipid mediators known as leukotrienes, which induce proinflammatory signaling through the activation of specific BLT and CysLT receptors. The ...

2006
D. M. P. Thomson Kerry Phelan Rosemarie Scanzano

We examined some of the metabolic events that regulate sensitizing cancer extract-induced leukocyte adherence inhi bition and found that human leukocytes adhere in a compara tively passive manner to glass in serum-free medium. Adher ence of leukocytes to glass did not require oxidative metabo lism, microtubules, microfilaments, or calcium entry, whereas leukocyte mobility excited by sensitizing...

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