The aim of this study was to assess radioprotective effects of quercetin and the ethanolic extract of propolis (EEP) in CBA mice exposed to a single radiation dose 4 Gy (60Co). The mice were treated with 100 mg kg(-1) quercetin or EEP a day for three consecutive days either before (pre-treatment) or after gamma-irradiation (therapy). Leukocyte count was determined in blood drawn from the tail v...

This study was performed to define the correlation between the level of consciousness based on Glasgow coma scale ( GCS), Glasgow outcome scale( GOS) and leukocyte count. Two hundred and thirty three patients ( female: 48, male: 185) ranged between 1-75 years old were studied. The results showed that there was a negative correlation between increasing leukocyte count and  GCS ( n=233.r= .0.3, p...

Patient Sex, age Symptoms No. of days from ingestion of fish to onset of symptoms No. of h from onset of symptoms to the start of therapy Albendazole therapy, no. of days (total no. of tablets) No. of h from the start of therapy to clinical and radiological resolution Results of the skin prick test for A. simplex Leukocyte count, cells/mL (% eosinophils) Level of specific IgE against A. simplex...

Chronic myeloid leukemia (CML) is a myeloproliferative malignancy due to the formation of BCR-ABL fusion gene in chronic leukemia. This condition causes excessive cell proliferation, resulting an increase number leukocytes. Tyrosine Kinase Inhibitor (TKI) first-line therapy that helps reduce percentage patients with study was conducted determine differences hematological profiles (hemoglobin le...

Inhibition of leukocyte adhesion to the vascular endothelium represents a novel and important approach for decreasing sickle cell disease (SCD) vaso-occlusion. Using a humanized SCD–mouse-model of tumor necrosis factor–induced acute vaso-occlusion, we herein present data demonstrating that short-term administration of either hydroxyurea or the phosphodiesterase 9 (PDE9) inhibitor, BAY736691, si...

the leukotrienes and prostaglandins are biologically active metabolites derived from arachidonic acid. the leukotrienes have a role in inflammatory diseases such as allergic rhinitis, inflammatory bowel disease and asthma. montelukast, a cysteinyl leukotriene receptor antagonist, is claimed to be effective in asthma. the present study aimed to assess the role of cysteinyl leukotriene receptor a...

during antigen capture and processing, mature dendritic cells (dc) express large amounts of peptide-mhc complexes and accessory molecules on their surface. we investigated the role of ifn-β in induction hla-g expression on the monocyte derived dc and cytokine profile in diabetes type 1. we accomplished secretary pattern and total cytokine production of the th1 cytokine (il-2, γifn) and th2 cyto...

BACKGROUND AND AIMS Secondary thrombocytosis is a clinical feature of unknown significance. In inflammatory bowel disease (IBD), thrombocytosis is considered a marker of active disease; however, iron deficiency itself may trigger platelet generation. In this study we tested the effect of iron therapy on platelet counts in patients with IBD-associated anemia. METHODS Platelet counts were analy...