نتایج جستجو برای: leukocyte telomere length

تعداد نتایج: 346584  

2013
Caitlin Mason Rosa-Ana Risques Liren Xiao Catherine R. Duggan Ikuyo Imayama Kristin L. Campbell Angela Kong Karen E. Foster-Schubert CY Wang Catherine M. Alfano George L. Blackburn Peter S. Rabinovitch Anne McTiernan

OBJECTIVE Investigate the effects of 12 months of dietary weight loss and/or aerobic exercise on leukocyte telomere length in postmenopausal women. DESIGN AND METHODS Four hundred and thirty nine overweight or obese women (50-75 years) were randomized to: (i) dietary weight loss (N = 118); (ii) aerobic exercise (N = 117), (iii) diet + exercise (N = 117), or (iv) control (N = 87). The diet int...

2015
Susan M. Mason Jennifer Prescott Shelley S. Tworoger Immaculata DeVivo Janet W. Rich-Edwards Gabriele Saretzki

OBJECTIVE Abuse victimization in childhood is associated with a variety of age-related cardiometabolic diseases, but the mechanisms remain unknown. Telomeres, which form the protective caps at the ends of chromosomes, have been proposed as measures of biological age, and a growing body of research suggests that telomere attrition may help to explain relationships between stress and cardiometabo...

2005
Stephen Cresswell Alexandra Coddington

2014
Masanori Enokido Akihito Suzuki Ryoichi Sadahiro Yoshihiko Matsumoto Fumikazu Kuwahata Nana Takahashi Kaoru Goto Koichi Otani

BACKGROUND There have been several reports suggesting that adverse childhood experiences such as physical maltreatment and long institutionalization influence telomere length. However, there has been no study examining the relationship of telomere length with variations in parental rearing. In the present study, we examined the relationship of leukocyte telomere length with parental rearing in ...

2012
Geraldine Aubert Gabriela M. Baerlocher Irma Vulto Steven S. Poon Peter M. Lansdorp

Telomerase activity is readily detectable in extracts from human hematopoietic stem and progenitor cells, but appears unable to maintain telomere length with proliferation in vitro and with age in vivo. We performed a detailed study of the telomere length by flow FISH analysis in leukocytes from 835 healthy individuals and 60 individuals with reduced telomerase activity. Healthy individuals sho...

Journal: :The American Journal of Clinical Nutrition 2013

Journal: :Arteriosclerosis, Thrombosis, and Vascular Biology 2011

2012
Qi Sun Ling Shi Jennifer Prescott Stephanie E. Chiuve Frank B. Hu Immaculata De Vivo Meir J. Stampfer Paul W. Franks JoAnn E. Manson Kathryn M. Rexrode

CONTEXT Whether a healthy lifestyle may be associated with longer telomere length is largely unknown. OBJECTIVES To examine healthy lifestyle practices, which are primary prevention measures against major age-related chronic diseases, in relation to leukocyte telomere length. DESIGN AND SETTING Cross-sectional analysis in the Nurses' Health Study (NHS). PARTICIPANTS The population consist...

Journal: :Cancer Epidemiology Biomarkers & Prevention 2017

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