BACKGROUND Potential association of leptin (LEP) gene polymorphisms has been suggested in the processes leading to breast cancer initiation and progression. We investigated whether genetic variations in the LEP -2548G/A gene are associated with risk of breast cancer. METHODS This case-control study consisted of 100 breast cancer cases and 100 control subjects without breast cancer that matche...

INTRODUCTION Leptin (LEP) and its receptor (LEPR) participate in the immunological response during infection. LEP serum levels rise during sepsis. In patients with peritonitis, an insufficient elevation in serum LEP is associated with an increased risk of death. As gene variants of LEP and LEPR have been associated with diverse pathologic conditions, we explored the association of genetic polym...

INTRODUCTION Laser treatment of benign prostatic hyperplasia (BPH) through enucleation techniques has become increasingly more utilized in the field of urology. Laser enucleation of the prostate (LEP) is a transurethral procedure that employs several different types of lasers to dissect the adenoma from the surgical capsule in a retrograde fashion. MATERIALS AND METHODS We review basic laser ...

Metabolic hormones have been associated with reproductive function modulation. Thus, the aim of this study was: (i) to characterize the immunolocalization, mRNA and protein levels of leptin (LEP), Ghrelin (GHR) and respective receptors LEPR and Ghr-R1A, throughout luteal phase; and (ii) to evaluate the role of LEP and GHR on progesterone (P4), prostaglandin (PG) E2 and PGF2α , nitric oxide (nit...

After a comment on the performance of LEP some highlights of the LEP1 and LEP2 physics programmes are reviewed. The talk concentrates on the precision measurements at the Z resonance, two fermion production above the Z, W + W − production, ZZ production, indirect limits on the Higgs mass, LEP contributions to the exploration of the CKM matrix, and on the LEP measurements of αs.

The status of the LEP precision measurements is reviewed, covering the electroweak measurements at the Z0, the studies of fermion pair production, and the totally new subject of W physics at LEP-2. The results presented here include both published and preliminary ones. These precision results are used to check the overall consistency of the Standard Model, and in its framework, constraints on i...

The bovine leptin (LEP) gene was widely used as a candidate gene for molecular selection to improve productivity traits of cattle. This study was carried out to identify single nucleotide polymorphisms (SNPs) in the LEP gene of Sumba Ongole (SO, Bos indicus) cows using sequencing method. A total of 31 animals were used in this study for analyses. Research showed that total of 16 SNPs w...