The aim of the present study was to evaluate the expression and effect of rat mitofusin-2 (rMfn2) in the ovaries and other organs in rats. Rat models were developed by the intraovarian microinjection of an rMfn2-overexpressing lentiviral vector. Lenti-green fluorescent protein (GFP)-rMfn2 was microinjected into rat ovaries at a dosage of 2×106 tuberculin units virosome (n=25) and lenti-GFP was ...

abstract in order to study the sensitivity of seven crops to total herbicide soil residue, an experiment was carried out under controlled conditions in 2009 at the college of agriculture, ferdowsi university of mashhad-iran. in this study 7 crops (pea, bean, lentil, corn, rape, beet and tomato), across 7 simulated soil residual concentration of total herbicide (0, 0.0002, 0.0005, 0.001, 0.002, ...

Baboon bone marrow was grafted into human immunodeficiency virus type 1-infected patients in the course of recent trials for AIDS treatment. Since the baboon genome harbors multiple copies of an endogenous oncovirus, chimeric lenti-oncoviruses could emerge in the xenotransplant recipient. To analyze the potential replication competence of hybrid viruses between different genera of retroviruses,...

L. BOTTONI 1,2, R. MASSA 1 and D. LENTI BOERO 3,4 1 Dipartimento di Scienze dell’Ambiente e del Territorio, Università degli Studi Milano Bicocca, Piazza della Scienza 1, I-20136 Milano, Italy 3 Facoltà di Scienze della Formazione, Università di Urbino, Via Saffi 15, I-60129 Urbino-PS, Italy 4 Laboratorio di Bioacustica e Analisi Comparativa del Comportamento e delle Funzioni Cognitive, Facoltà...

In the present study, posterior spiracles of laboratory-reared fourth instar larvae of Lutzomyia longipalpis, L. migonei, L. lenti, and L. whitmani (Diptera: Psychodidae) of the State of Ceará, Brazil, were examined under scanning electron microscopy. The number of papillae of spiracles examined varied according to the species examined, but no intraspecific differences were found. The importanc...

Hemoglobinopathies are caused by abnormal structure or synthesis of hemoglobin chains and represent serious monogenic disorders. A new study demonstrates that lentiviral vectors can express clinically relevant levels of human transgenic beta-globin in red cells of xenografted mice. While some safety concerns must be addressed, this study is an important step toward potential clinical trials of ...

Target audience This work should be of interest to people studying astroglial reactivity and neurodegenerative processes using proton spectroscopy and CEST imaging. Purpose Astrocytes are the most abundant glial cells and are key players in brain function. In response to pathological conditions such as neurodegenerative diseases or ischemia, astrocytes display morphological and physiological ch...