Oral anticoagulation with warfarin is a cornerstone in the prevention of systemic thromboembolism in patients with atrial fibrillation. It reduces the risk of stroke by 67% compared with no antithrombotic therapy and by 36% compared with aspirin. The downside of anticoagulation is increased risk of major bleeding which amounts to 1% per year. Therefore, careful selection of patients for oral an...

BACKGROUND Mean platelet volume has been associated with stroke in patients with atrial fibrillation. However, its role as a predictor of left atrial stasis, assessed by transesophageal echocardiography, in patients with non-valvular atrial fibrillation has not yet been clarified. METHODS Single center cross-sectional study comprising 427 patients admitted to the emergency department due to s...

Echocardiographic studies were performed in 22 patients with atrial fibrillation and atrial flutter. In atrial flutter, the echocardiograms consistently demonstrated regular undulatory waves of the posterior left atrial wall and upper left interventricular septum coinciding with each flutter wave of the electrocardiogram. The mitral valve was slightly reopened by each flutter wave occurring aft...

Recognition that the initiation of atrial fibrillation often is dependent on arrhythmogenic foci within the pulmonary veins1 opened a new chapter in our understanding of the mechanisms of atrial fibrillation, which in turn has led to dramatic improvements in our ability to ablate atrial fibrillation. Based on experimental studies and clinical studies that used a variety of catheter and surgical...

SUMMARY Direct current conversion of atrial fibrillation has been attempted in 60 consecutive patients following prosthetic mitral valve replacement (Starr-Edwards prosthesis). Sinus rhythm was attained and persisted for at least 24 hours after the procedure in 68% (41 patients) and 40% of the entire group (24 patients) were still in normal sinus rhythm an average of 10 months later. Successful...

AIM The aim of this prospective study was to assess the presence of sinus rhythm and atrial transport function after surgical ablation of atrial fibrillation using cryoenergy, and to evaluate predictors of the success of the procedure. METHODS Between January 2005 and September 2006, 100 consecutive patients underwent left atrial cryoablation as a concomitant surgical procedure (46 patients w...

background: atrial fibrillation is a common arrhythmia in patients with rheumatic mitral and other valve diseases who are candidates for valve repair surgeries. conversion of rhythm to sinus has positive effects on quality of life and lower use of medications. the aim of this clinical study was to evaluate the effectiveness of the radiofrequency ablation maze iii procedure in the treatment of a...

a 54-year-old man referred to our center with barlow’s disease and severe mitral regurgitation. he had atrial fibrillation (af) rhythm, with a mildly enlarged left atrium (la). transesophageal echocardiography (tee) showed no clot in the la and la appendage; there was only mild spontaneous echo contrast in the la appendage. the patient underwent mitral valve repair and the maze operation, durin...

BACKGROUND Heart failure and stroke are major causes of morbidity and mortality in older people. Angiotensin converting enzyme inhibitors improve symptoms and survival in left ventricular systolic dysfunction. Anticoagulants are effective in stroke prevention in atrial fibrillation with aspirin being a less effective alternative. OBJECTIVES To determine the prevalence of left ventricular syst...

OBJECTIVES The prognostic significance of preoperative atrial fibrillation on mitral valve replacement remains unclear. The aim of this study was to explore the effects of the presence of preoperative atrial fibrillation on mortality and cardiovascular outcomes of mitral valve replacement for rheumatic valve disease. METHODS A retrospective analysis was performed on a total of 793 patients wh...