The optically transparent larval zebrafish is ideally suited for in vivo analyses of neural circuitry controlling visually guided behaviors. However, there is a lack of information regarding specific cell types in the major retinorecipient brain region of the fish, the optic tectum. Here we report the characterization of three previously unidentified tectal cell types that are specifically labe...

Our previous studies have shown that when slices of the rat superior colliculus (SC) are exposed to a solution containing 10 microM bicuculline and a low concentration of Mg2+ (0.1 mM), most neurons in the intermediate gray layer (stratum griseum intermediale; SGI), wide-field vertical (WFV) cells in the optic layer (stratum opticum; SO), and a minor population of neurons in the superficial gra...

Pitx2, a paired-like homeodomain transcription factor, is expressed in post-mitotic neurons within highly restricted domains of the embryonic mouse brain. Previous reports identified critical roles for PITX2 in histogenesis of the hypothalamus and midbrain, but the cellular identities of PITX2-positive neurons in these regions were not fully explored. This study characterizes Pitx2 expression w...

A new communications environment, driven largely by the Internet and World Wide Web, is rapidly changing the economic, social, and political landscape. According to recent surveys, nearly seven in ten Americans (68 percent) now use computers at least "occasionally," six in ten (59 percent) have computers in their homes, and more than half (55 percent) have access to the Internet, 43 percent of ...