Objective: To see the dose dependent effects of zinc chloride on the short-term and long-term memory in a shuttle box (rats). Methodology: Six pair adult wistar rats were taken for this experiment. One group of pregnant rats received a daily oral dose of 20mg/kg Zn as zinc chloride and the remaining groups received a daily oral dose of (30, 50, 70,100mg/kg) zinc chloride for two weeks by gavage...

Zinc chloride solution injected into the testes of 49 Syrian hamsters during the early spring months resulted in two embryonal carcinomas of the testis found at necropsy 10 weeks later. The zinc chloride injections were made during the period of rapid seasonal gonadal growth when spermatogonial division is activated and resulted in areas of coagulative necrosis occupying about 25% of each testi...

The objective of this study was to evaluate the effect of heavy metals, at environmentally relevant concentrations, on the immune response of rainbow trout. Trout were exposed for 30 d to cadmium chloride (CdCl2), mercuric chloride (HgCl2), or zinc chloride (ZnCl2) either individually or in combinations: CdCl2/HgCl2, CdCl2/ZnCl2, HgCl2/ZnCl2, or CdCl2/HgCl2/ZnCl2. Following the 30-d exposure, p...

Zinc chlorochromate nonahydrate is easily prepared from the aqueous solution of chromium trioxide and zinc chloride in quantitative yield. This oxidant, in methylene chloride and at room temperature, oxidizes thiols to their disulfides. Acetals and thioacetals are deprotected to their corresponding carbonyl compounds. Sulfides are selectively converted to ther sulfoxides or sulfones. Arylox...

A series of geometry, frequency, and energy calculations of chloroaquazinc(II) complexes were carried out at up to the MP2/6-31+G* level. A thorough examination of all species up to and including hexacoordinate species, and with up to six chlorides, was carried out. The structures of the complexes are compared with experimental data where available. The solution chemistry of zinc(II) in the pre...

In response to various environmental stresses including heavy metals, the c-Jun N-terminal kinase (JNK) is phosphorylated and then it phosphorylates c-Jun protein. In the present study, effects of mercury chloride (HgCl2) on JNK signalling pathway were examined in LLC-PK1 cells. When exposed to 10 or 20 microM HgCl2, the level of phosphorylated JNK and the activity of JNK assayed in vitro using...

Thioltransferase, also known as glutaredoxin, is an enzyme that catalyzes the reduction of a variety of disulfide compounds. In Schizosaccharomyces pombe, two thioltransferases were reported and the cDNA of one of the thioltransferases (thioltransferase-1) was cloned. Using a Northern blot assay, we investigated the thioltransferase transcription in response to various stress conditions. When t...