The aim of this study was to investigate the effect of chlorfenvinphos administered at a single dose of 0.02 LD50 on the activity of serum of liver damage indicatory enzymes, such as β-glucoronidase (BGR), acid phosphatase (AcP) and alanine and aspartate aminotransferases (ALT and AST), as well as on the activities of superoxide dismutase (SOD) and catalase (CAT) in erythrocytes and liver. The ...

background: currently available radioprotectors are poorly tolerated in man and the general use of aminothiols is compromised by their side effects. this study was carried out to test and compare the radioprotective potential of cimetidine and famotidine against lethally gamma irradiated nmri mice. materials and methods: adult male nmri mice in groups of 10 were exposed to various doses of gamm...

Genetic variation is needed for developing new superior varieties in plant breeding. of chili plants could be increased by inducing mutation with gamma rays irradiation. The aim this study was to determine radiosensitivity two local pepper calculating the lethal dose values at LD20 and LD50. Chili (Capsicum frutescens L.) seeds origin from Tulungagung Ponorogo were irradiated cobalt-60 doses of...

Mice inoculated either subcutaneously (s.c.) or intradermally (i.d.) with a sublethal dose of Francisella tularensis LVS are immune to a lethal intraperitoneal (i.p.) or intravenous (i.v.) challenge of LVS. Here, we show that this immunity developed quite rapidly: mice given a sublethal dose of live LVS s.c. or i.d. (but not i.v.) withstood lethal i.p., i.v., or i.d. challenge as early as 2 day...

Methanol extracts of different plants namely, Trichodesma africanum (Boraginaceae), Cleome rupicola (Capparceae) and Ochradenus baccatus (Resedaceae), were tested for larvicidal activity against 4 instar larvae of Aedes caspius and Culex pipiens mosquitoes. All plant extracts tested against Ae. caspius showed 100% mortality at 10μg/ml except the stem of O. baccatus which showed 90% mortality. H...

The embryonic/fetotoxic effects of DEHP on pregnant mice (ddY-Slc female x CBA male) were studied. DEHP was administered orally in dosages of 0.05 ml/kg to 30.0 mg/kg on day 6, 7, 8, 9 or 10 of gestation. A single administration of DEHP over 0.1 ml/kg (1/300 of LD50) on day 7 of gestation decreased the numbers and the body weight of living fetuses, whereas no significant changes in the numbers ...

The essential oil of Clausena anisum-olens (Blanco) Merr. showed strong contact toxicity and repellency against Lasioderma serricorne and Liposcelis bostrychophila adults. The components of the essential oil obtained by hydrodistillation were determined by gas chromatography-mass spectrometry. It was found that the main components were myristicin (36.87%), terpinolene (13.26%), p-cymene-8-ol (1...

Venom from the Mohave rattlesnake, Crotalus scutulatus scutulatus, has been reported to be either: (1) neurotoxic; (2) hemorrhagic, or both (3) neurotoxic and hemorrhagic. In this study, 14 Mohave rattlesnakes from Arizona and Texas (USA) were analyzed for the presence of disintegrins and Mojave toxin. All venom samples were analyzed for the presence of hemorrhagic, proteolytic and disintegrin ...

In this study, we performed ecotoxicity tests of sodium arsenite on soil invertebrate Eisenia fetida. Initially, broad range of sodium arsenite (0.1, 1, 10, 100mg/ml) was tested for mortality of E. fetida after 24 hours in filter paper test. The narrow range doses (0-1mg/ml) were further tested to determine the EC50 and LD50. The EC50 dose of sodium arsenite was considered at which 50% of earth...

Two mineral oils and 12 linear primary alcohols were studied, alone and in combination, to determine their contact toxicity to adult German cockroaches, Blattella germanica (L.) (Dictyoptera: Blattellidae). The more toxic oil, PD23 (LD50 = 1.45 mg per cockroach) was used for combination studies. Alcohols with carbon chain lengths of C3 and C8 through C12 were the most toxic, with LD50 values ra...