We have recently shown that conservation and differentiation of primitive human hematopoietic progenitors in in vitro long-term bone marrow cultures (LTBMC) occurs to a greater extent when hematopoietic cells are grown separated from the stromal layer than when grown in direct contact with the stroma. This finding suggests that hematopoiesis may depend mainly on soluble factors produced by the ...

We have used a computer simulation system to examine formation of the chick primitive streak and to test the proposal (Wei and Mikawa Development 127 (2000) 87) that oriented cell division could account for primitive streak elongation. We find that this proposal is inadequate to explain elongation of the streak. In contrast, a correctly patterned model streak can be generated if two putative me...

A new concept using different display layer primitives for light field approximation is presented. For each primitive, a mathematical notation for the light transport operator is defined. Based on that, a decomposition algorithm rendering a light field into a multi-layered plenoptic display is described and verified by a physical prototype. Author

Graphite may be viewed as a low-surface-energy carbon allotrope with little layer-layer interaction. Other low-surface-energy allotropes but with much stronger layer-layer interaction may also exist. Here, we report a first-principles prediction for one of the known carbon allotropes, bcc-C6 (a body centered carbon allotrope with six atoms per primitive unit), that should have exceptionally low...

‎given a finite non-cyclic group $g$‎, ‎call $sigma(g)$ the smallest number of proper subgroups of $g$ needed to cover $g$‎. ‎lucchini and detomi conjectured that if a nonabelian group $g$ is such that $sigma(g) < sigma(g/n)$ for every non-trivial normal subgroup $n$ of $g$ then $g$ is textit{monolithic}‎, ‎meaning that it admits a unique minimal normal subgroup‎. ‎in this paper we show how thi...

A set of model equations for water wave propagation is derived by piecewise integration of the primitive equations of motion through N arbitrary layers. Within each layer, an independent velocity profile is determined. Depth-averaged and ‘‘extended’’ versions of the multi-layer model are presented and compared. With N separate velocity profiles, matched at the interfaces of the layers, the resu...

Anteroposterior (AP) polarity in the mammalian embryo is specified during gastrulation when naive progenitor cells in the primitive ectoderm are recruited into the primitive streak to form mesoderm and endoderm. At the opposite pole, this process is inhibited by signals previously induced in distal visceral endoderm (DVE). Both DVE and primitive streak formation, and hence positioning of the AP...

The yolk sac (YS) is the main source of embryonic nutrition during the period when the placenta has not yet formed. It is also responsible for hematopoiesis because the blood cells develop from it as part of the primitive embryonic circulation. The objective of this study was to characterize the transitional area between the YS and primitive gut using the techniques of light microscopy, transmi...