The aim of the study was to evaluate the influence of surgical trauma on systemic inflammation and immune response correlating preoperative and postoperative cytokine levels in patients undergoing laparotomy versus laparoscopic cholecystectomy. Seventy patients with chronic, symptomatic cholelithiasis confirmed by ultrasonography, without presence of cancer or signs of acute cholecystitis were ...

BACKGROUND In the developmental stage of laparoscopic cholecystectomy (LC) it was considered 'unsafe' or 'technically difficult' to perform laparoscopic cholecystectomy for acute cholecystitis (AC). With increasing experience in laparoscopic surgery, a number of centers have reported on the use of laparoscopic cholecystectomy for acute cholecystitis, suggesting that it is technically feasible b...

BACKGROUND Pulmonary complications remain a leading cause of morbidity after major abdominal operations. OBJECTIVE To compare pulmonary function and the frequency of pulmonary complications after laparoscopic cholecystectomy (LC) and open cholecystectomy (OC). METHODS Fifty-five patients with symptomatic gallstone disease undergoing elective cholecystectomy (LC 40, OC 15) under general anes...

Background: Laparoscopic cholecystectomy (LC) is the most practiced procedure in general surgery worldwide. It nowadays optimum surgical for symptomatic gallbladder lithiasis. Nevertheless, it should not be underestimated since vascular and biliary duct injuries are uncommon, with devastating consequences. This study aimed to advise best technical approach LC according intraoperative situation ...

BACKGROUND AND OBJECTIVES Gallstones are twice as common in cirrhotic patients as in the general population. Although laparoscopic cholecystectomy (LC) has become the gold standard for symptomatic gallstones, cirrhosis has been considered an absolute or relative contraindication. Many authors have reported on the safety of LC in cirrhotic patients. We reviewed our patients retrospectively and a...

BACKGROUND The pathological boundary of acute cholecystitis (AC) between early edematous and late chronic fibrotic inflammation beyond 72 h is well-described. Early laparoscopic cholecystectomy (ELC) is safe in AC but the timing still remains controversial. The aim of this study was to analyze the impact of the duration of symptoms on clinical severity, pathology and outcome in patients who und...

Gallstone disease is the pathologic state of stones or calculi within the gall bladder lumen and biliary tree. A common digestive disorder worldwide, worldwide occurrence varies from 6-20%. The definitive management of symptomatic gallstones is surgical. The two surgical approaches are conventional and laparoscopic. Important intraoperative considerations during laparoscopic cholecystectomy inc...

Background: One of the most commonly performed surgeries globally is Laparoscopic Cholecystectomy (LC) which gold standard surgical procedure for removal gallbladder. It provides numerous benefits over open cholecystectomy but has also shown higher complication rates. Therefore, a system devised pre operative assessment intra difficulty level should be adopted to help with preparedness complica...

OBJECTIVE A descriptive analysis of day-case laparoscopic cholecystectomy (ALC) in a cohort of 1,600 consecutive patients performed in Instituto de Cirugía y Aparato Digestivo (ICAD), Clínica Quirón de Valencia in the period 1997-2010. PATIENTS AND METHODS Prospective observational study of 1,601 consecutive patients undergoing elective laparoscopic cholecystectomy (LC) provided by the region...

Laparoscopic cholecystectomy (LC) was attempted in 847 patients, 823 (97.2%) were completed laparoscopically and 24 (2.8%) had to be converted to open cholecystectomy (OC). Acute cholecystitis was the commonest reason for conversion (13 out of 24 patients). Patients who had acute cholecystitis are five times at risk for conversion to open than other patients with non-acute cholecystitis (p< 0.0...